Acorafloxacin, also known as Avarofloxacin, JNJ-Q2 and JNJ-32729463, is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia. Specifically, JNJ-Q2 is being actively studied for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections.
MedKoo Cat#: 319666
Name: Acorafloxacin free base
CAS#: 878592-87-1 (free base)
Chemical Formula: C21H23F2N3O4
Exact Mass: 419.1657
Molecular Weight: 419.43
Elemental Analysis: C, 60.14; H, 5.53; F, 9.06; N, 10.02; O, 15.26
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 100.0 | 238.42 |
The following data is based on the product molecular weight 419.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
