Indimilast is a phosphodiesterase IV inhibitor. Phosphodiesterase (PDE) inhibitors modulate lung inflammation and cause bronchodilation by increasing intracellular cyclic adenosine 3', 5'-monophosphate in airway smooth muscle and inflammatory cells. PDE-4 inhibitor (PDE4I) is potential useful in chronic obstructive pulmonary disease (COPD).
MedKoo Cat#: 319635
Name: Indimilast
CAS#: 1038825-85-2
Chemical Formula: C37H40FN7O3S
Exact Mass: 681.2897
Molecular Weight: 681.83
Elemental Analysis: C, 65.18; H, 5.91; F, 2.79; N, 14.38; O, 7.04; S, 4.70
The following data is based on the product molecular weight 681.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
