MedKoo Cat#: 407235 | Name: LG190155

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LG190155 is a moderately potent VDR agonist. Vitamin D receptor (VDR) agonists are well known for their capacity to control calcium and bone metabolism and to regulate growth and differentiation of many cell types.

Chemical Structure

LG190155
LG190155
CAS# 233268-78-5

Theoretical Analysis

MedKoo Cat#: 407235

Name: LG190155

CAS#: 233268-78-5

Chemical Formula: C31H44O4

Exact Mass: 480.3240

Molecular Weight: 480.69

Elemental Analysis: C, 77.46; H, 9.23; O, 13.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LG190155; LG-190155; LG 190155; CAS# 233268-78-5
IUPAC/Chemical Name
1,1'-((pentane-3,3-diylbis(2-methyl-4,1-phenylene))bis(oxy))bis(3,3-dimethylbutan-2-one)
InChi Key
WBLVHHHWMJPSGY-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H44O4/c1-11-31(12-2,23-13-15-25(21(3)17-23)34-19-27(32)29(5,6)7)24-14-16-26(22(4)18-24)35-20-28(33)30(8,9)10/h13-18H,11-12,19-20H2,1-10H3
SMILES Code
CCC(C1=CC=C(OCC(C(C)(C)C)=O)C(C)=C1)(C2=CC=C(OCC(C(C)(C)C)=O)C(C)=C2)CC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
LG190155 is a moderately potent VDR agonist.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 480.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Swann SL, Bergh J, Farach-Carson MC, Ocasio CA, Koh JT. Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor. J Am Chem Soc. 2002 Nov 20;124(46):13795-805. PubMed PMID: 12431109.