Synonym
Apodol; Alidine; Leritin; Leritine; Nipecotan
IUPAC/Chemical Name
ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
InChi Key
LKYQLAWMNBFNJT-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28N2O2/c1-2-26-21(25)22(19-6-4-3-5-7-19)13-16-24(17-14-22)15-12-18-8-10-20(23)11-9-18/h3-11H,2,12-17,23H2,1H3
SMILES Code
CCOC(=O)C1(CCN(CC1)CCC2=CC=C(C=C2)N)C3=CC=CC=C3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
352.47
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Moss JH. Anileridine-induced delirium. J Pain Symptom Manage. 1995 May;10(4):318-20. PubMed PMID: 7541439.
2: Xu YQ, Fang HJ, Xu YX, Duan HJ, Wu Y. [Studies on the analysis of anileridine, levorphanol, nalbuphine and ethamivan in urine]. Yao Xue Xue Bao. 1991;26(8):606-10. Chinese. PubMed PMID: 1805523.
3: Yrjölä H, Heinonen J, Tuominen M, Heikkilä J. Comparison of haemodynamic effects of pethidine and anileridine in anaesthetised patients. Acta Anaesthesiol Scand. 1981 Oct;25(5):412-5. PubMed PMID: 6896113.
4: Ecker RI. Contact dermatitis to anileridine. Contact Dermatitis. 1980 Dec;6(7):495. PubMed PMID: 6894270.
5: Leander JD. Comparison of morphine, meperidine, anileridine, and alphaprodine on schedule-controlled responding and analgesia. Pharmacol Biochem Behav. 1980 May;12(5):797-801. PubMed PMID: 6104822.
6: Leander JD. Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons. J Pharmacol Exp Ther. 1978 Sep;206(3):624-35. PubMed PMID: 581295.
7: Dykstra LA, Leander JD. Electric shock titration: effects of meperidine, anileridine and alphaprodine. Pharmacol Biochem Behav. 1978 Apr;8(4):387-9. PubMed PMID: 97674.
8: Freeman DS, Gjika HB, Van Vunakis H. Radioimmunoassay for normeperidine: studies on the N-dealkylation of meperidine and anileridine. J Pharmacol Exp Ther. 1977 Oct;203(1):203-12. PubMed PMID: 578528.
9: Tuominen M. Comparison of anileridine and pethidine in patients with pain following upper abdominal surgery. Ann Chir Gynaecol. 1976;65(3):207-15. PubMed PMID: 786135.
10: Tuominen M. Comparison of the effect of anileridine and pethidine on the intracholedochal pressure during constant fluid perfusion. Acta Anaesthesiol Scand. 1976;20(2):177-82. PubMed PMID: 779392.
