Tymazoline, an imidazoline-derived α1-adrenergic agonist, induces vasoconstriction to reduce nasal congestion. It directly stimulates vascular smooth muscle contraction, decreasing blood flow and swelling. Used topically, it treats rhinitis and sinusitis with minimal systemic absorption.
MedKoo Cat#: 318963
Name: Tymazoline HCl
CAS#: 28120-03-8 (hydrochloride)
Chemical Formula: C14H21ClN2O
Exact Mass: 0.0000
Molecular Weight: 268.79
Elemental Analysis: C, 62.56; H, 7.88; Cl, 13.19; N, 10.42; O, 5.95
The following data is based on the product molecular weight 268.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
