BYK204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively). BYK204165 was found to be 100-fold more selective for PARP-1. BYK204165 might be novel and valuable tool for investigating PARP-1-mediated effects.
MedKoo Cat#: 407143
Name: BYK204165
CAS#: 1104546-89-5
Chemical Formula: C15H12N2O2
Exact Mass: 252.0899
Molecular Weight: 252.27
Elemental Analysis: C, 71.42; H, 4.79; N, 11.10; O, 12.68
The following data is based on the product molecular weight 252.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
