Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is the ester of epigallocatechin and gallic acid, and is a type of catechin. EGCG is the most abundant catechin in tea and is a potent antioxidant that may have therapeutic applications in the treatment of many disorders (e.g. cancer). It is found mainly in white tea, green tea and, in smaller quantities, black tea; during black tea production, the catechins are mostly converted to theaflavins and thearubigins, and theabrownins. It is also found in various vegetables, nuts, as well as carob powder at 109 mg per 100g.
MedKoo Cat#: 600133
Name: Epigallocatechin gallate
CAS#: 989-51-5 (gallate)
Chemical Formula: C22H18O11
Exact Mass: 458.0849
Molecular Weight: 458.37
Elemental Analysis: C, 57.65; H, 3.96; O, 38.40
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| DMF | 30.0 | 65.45 | ||
| Ethanol | 56.0 | 122.17 | ||
| PBS (pH 7.2) | 25.0 | 54.00 | ||
| Water | 38.9 | 84.78 | ||
| DMSO | 48.2 | 105.18 |
The following data is based on the product molecular weight 458.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
