20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. It is therefore one of the most common moulting hormones in insects, crabs, etc. It is also a phytoecdysteroid produced by various plants, including Cyanotis vaga, where its purpose is presumably to disrupt the development and reproduction of insect pests. In arthropods, 20-hydroxyecdysone acts through the ecdysone receptor. Although mammals lack this receptor, 20-hydroxyecdysone may affect mammalian (including human) biological systems in vitro, but there is uncertainty whether any in vivo or physiological effects occur. 20-Hydroxyecdysone is an ingredient of some supplements that aim to enhance physical performance, but there is no clinical evidence for this effect. (Source: http://en.wikipedia.org/wiki/Ecdysterone).
MedKoo Cat#: 600130
Name: Ecdysterone
CAS#: 5289-74-7
Chemical Formula: C27H44O7
Exact Mass: 480.3087
Molecular Weight: 480.63
Elemental Analysis: C, 67.47; H, 9.23; O, 23.30
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 75.3 | 156.73 | |
| DMF | 30.0 | 62.42 | |
| Ethanol | 60.5 | 125.88 | |
| PBS (pH 7.2) | 10.0 | 20.81 |
The following data is based on the product molecular weight 480.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
