MedKoo Cat#: 300149 | Name: Estrone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. Estrone is the only estrogen which is present in any quantity in post-menopausal women. (Source: http://en.wikipedia.org/wiki/Estrone).

Chemical Structure

Estrone
Estrone
CAS#53-16-7

Theoretical Analysis

MedKoo Cat#: 300149

Name: Estrone

CAS#: 53-16-7

Chemical Formula: C18H22O2

Exact Mass: 270.1620

Molecular Weight: 270.37

Elemental Analysis: C, 79.96; H, 8.20; O, 11.84

Price and Availability

Size Price Availability Quantity
2g USD 250.00 2 Weeks
5g USD 450.00 2 Weeks
10g USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
Estrone; Oestrone; Folliculin; Theelin
IUPAC/Chemical Name
(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one
InChi Key
DNXHEGUUPJUMQT-CBZIJGRNSA-N
InChi Code
InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1
SMILES Code
O=C1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@]12C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO.
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 270.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Remesar X, Fernández-López JA, Alemany M. Oleoyl-estrone. Med Res Rev. 2012 Nov;32(6):1263-91. doi: 10.1002/med.20240. Epub 2011 Feb 1. Review. PubMed PMID:   21287573.