Alogliptin benzoate is a DPP-4 inhibitor used for the treatment of Type 2 diabetes. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
MedKoo Cat#: 314210
Name: Alogliptin benzoate
CAS#: 850649-62-6 (benzoate)
Chemical Formula: C25H27N5O4
Exact Mass: 0.0000
Molecular Weight: 461.52
Elemental Analysis: C, 65.06; H, 5.90; N, 15.17; O, 13.87
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| DMSO | 39.4 | 85.30 | ||
| DMF | 0.1 | 0.22 | ||
| PBS (pH 7.2) | 10.0 | 21.67 | ||
| Water | 2.0 | 4.33 |
The following data is based on the product molecular weight 461.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
