PF-4942847 is a novel oral Hsp90 inhibitor, which is a candidate for clinical development in TNBC by collaboratively targeting multiple signaling pathways. In addition, AKT degradation in PBLs may serve as a biomarker in clinical development.
MedKoo Cat#: 401691
Name: PF-4942847
CAS#: 1046859-34-0
Chemical Formula: C20H18Cl2F3N7O2
Exact Mass: 515.0851
Molecular Weight: 516.30
Elemental Analysis: C, 46.53; H, 3.51; Cl, 13.73; F, 11.04; N, 18.99; O, 6.20
The following data is based on the product molecular weight 516.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
