MedKoo Cat#: 129034 | Name: Morpholino T Phosphoramidite
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Morpholino T phosphoramidite is a nucleoside building block that has been used in the synthesis of morpholino oligonucleotides.

Chemical Structure

Morpholino T Phosphoramidite
Morpholino T Phosphoramidite
CAS#1037305-43-3

Theoretical Analysis

MedKoo Cat#: 129034

Name: Morpholino T Phosphoramidite

CAS#: 1037305-43-3

Chemical Formula: C40H50N5O7P

Exact Mass: 743.3448

Molecular Weight: 743.84

Elemental Analysis: C, 64.59; H, 6.78; N, 9.42; O, 15.06; P, 4.16

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
25mg USD 1,050.00 2 Weeks
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Related CAS #
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Synonym
Morpholino T Phosphoramidite
IUPAC/Chemical Name
3-((((2S,6R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-6-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)morpholino)(diisopropylamino)phosphaneyl)oxy)propanenitrile
InChi Key
XEHSKNSZPOYQCS-KKAJOCKXSA-N
InChi Code
InChI=1S/C40H50N5O7P/c1-28(2)45(29(3)4)53(51-23-11-22-41)43-25-36(52-37(26-43)44-24-30(5)38(46)42-39(44)47)27-50-40(31-12-9-8-10-13-31,32-14-18-34(48-6)19-15-32)33-16-20-35(49-7)21-17-33/h8-10,12-21,24,28-29,36-37H,11,23,25-27H2,1-7H3,(H,42,46,47)/t36-,37+,53?/m0/s1
SMILES Code
COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@H]3O[C@H](CN(C3)P(N(C(C)C)C(C)C)OCCC#N)N4C=C(C(NC4=O)=O)C)C5=CC=CC=C5)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 743.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Langner, H.K., Jastrzebska, K., and Caruthers, M.H. Synthesis and characterization of thiophosphoramidate morpholino oligonucleotides and chimeras. J. Am. Chem. Soc. 142(38), 16240-16253 (2020).