MedKoo Cat#: 146388 | Name: Carbaril

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carbaryl is a widely used carbamate insecticide applied in agriculture, home gardening, and public health to control pests on crops, lawns, and ornamental plants. It works by inhibiting the enzyme acetylcholinesterase, which is essential for nerve function in insects, leading to the accumulation of acetylcholine at synapses and ultimately causing paralysis and death. Due to its broad-spectrum activity and relatively low persistence in the environment, it has been favored for pest management.

Chemical Structure

Carbaril
Carbaril
CAS#63-25-2

Theoretical Analysis

MedKoo Cat#: 146388

Name: Carbaril

CAS#: 63-25-2

Chemical Formula: C12H11NO2

Exact Mass: 201.0790

Molecular Weight: 201.23

Elemental Analysis: C, 71.63; H, 5.51; N, 6.96; O, 15.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Carbaril; Carbaryl;
IUPAC/Chemical Name
naphthalen-1-yl methylcarbamate
InChi Key
CVXBEEMKQHEXEN-UHFFFAOYSA-N
InChi Code
1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
SMILES Code
CNC(=O)OC1=C2C=CC=CC2=CC=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 201.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Davies P. Carbaril for head lice. Lancet. 2000 Sep 2;356(9232):855. doi: 10.1016/S0140-6736(05)73433-4. PMID: 11022953. 2: Gallo MA. 'Tis the season. J Med Soc N J. 1983 May;80(5):329-30. PMID: 6408263. 3: Wu P, Chen Z, Zhang Y, Wang Y, Zhu F, Cao B, Jin L, Hou Y, Wu Y, Li N. Carbaryl waste-water treatment by Rhodopseudomonas sphaeroides. Chemosphere. 2019 Oct;233:597-602. doi: 10.1016/j.chemosphere.2019.05.237. Epub 2019 May 27. Retraction in: Chemosphere. 2020 Oct;257:127394. doi: 10.1016/j.chemosphere.2020.127394. PMID: 31195264. 4: Cranmer MF. Carbaryl. A toxicological review and risk analysis. Neurotoxicology. 1986 Spring;7(1):247-328. PMID: 3086783. 5: Phale PS, Shah BA, Malhotra H. Variability in Assembly of Degradation Operons for Naphthalene and its derivative, Carbaryl, Suggests Mobilization through Horizontal Gene Transfer. Genes (Basel). 2019 Jul 27;10(8):569. doi: 10.3390/genes10080569. PMID: 31357661; PMCID: PMC6723655. 6: Carbaryl against lice. Drug Ther Bull. 1982 Jul 23;20(15):59-60. PMID: 6814883. 7: Snyder MN, Henderson WM, Glinski DA, Purucker ST. Differentiating metabolomic responses of amphibians to multiple stressors. Sci Total Environ. 2022 Sep 10;838(Pt 3):155666. doi: 10.1016/j.scitotenv.2022.155666. Epub 2022 May 19. PMID: 35598671; PMCID: PMC9875051. 8: Mount ME, Oehme FW. Carbaryl: a literature review. Residue Rev. 1981;80:1-64. doi: 10.1007/978-1-4612-5913-8_1. PMID: 6791256. 9: Gunasekara AS, Rubin AL, Goh KS, Spurlock FC, Tjeerdema RS. Environmental fate and toxicology of carbaryl. Rev Environ Contam Toxicol. 2008;196:95-121. doi: 10.1007/978-0-387-78444-1_4. PMID: 19025094. 10: Sooksawat N, Inthorn D, Chittawanij A, Vangnai A, Kongtip P, Woskie S. Phytoextraction Potential of Sunn Hemp, Sunflower, and Marigold for Carbaryl Contamination: Hydroponic Experiment. Int J Environ Res Public Health. 2022 Dec 8;19(24):16482. doi: 10.3390/ijerph192416482. PMID: 36554374; PMCID: PMC9779587. 11: Shabanov M, Toshkov A, Georgiev D, Ibrishimov N. Vliianie na pestitsida karbaril (sevin) vŭrkhu khoda na eksperimentalna infektsiia u plŭkhove s Erysipelothrix rhusiopathiae [Effect of the pesticide carbaryl (sevin) on the course of experimental Erysipelothrix rhusiopathiae infection in rats]. Vet Med Nauki. 1983;20(5-6):9-15. Bulgarian. PMID: 6419448. 12: Faria M, Bellot M, Bedrossiantz J, Ramírez JRR, Prats E, Garcia-Reyero N, Gomez-Canela C, Mestres J, Rovira X, Barata C, Oliván LMG, Llebaria A, Raldua D. Environmental levels of carbaryl impair zebrafish larvae behaviour: The potential role of ADRA2B and HTR2B. J Hazard Mater. 2022 Jun 5;431:128563. doi: 10.1016/j.jhazmat.2022.128563. Epub 2022 Feb 24. PMID: 35248961. 13: Hao H, Zhu J, Yang B, Peng L, Lou S. Ovalbumin-coated gold nanoparticles with interesting colloidal stability for colorimetric detection of carbaryl in complex media. Food Chem. 2023 Mar 1;403:134485. doi: 10.1016/j.foodchem.2022.134485. Epub 2022 Oct 1. PMID: 36358087. 14: Jiao W, Ding G, Wang L, Liu Y, Zhan T. Polyaniline functionalized CoAl- layered double hydroxide nanosheets as a platform for the electrochemical detection of carbaryl and isoprocarb. Mikrochim Acta. 2022 Jan 29;189(2):78. doi: 10.1007/s00604-022-05183-y. PMID: 35094165. 15: Joshi R, Adhikari S, Pil Son J, Jang Y, Lee D, Cho BK. Au nanogap SERS substrate for the carbaryl pesticide determination in juice and milk using chemomterics. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Sep 5;297:122734. doi: 10.1016/j.saa.2023.122734. Epub 2023 Apr 13. PMID: 37080052. 16: Tong H, Xiong J. Effect of carbaryl contamination on bioretention system nitrogen removal performance. Environ Sci Pollut Res Int. 2024 Sep;31(44):56227-56235. doi: 10.1007/s11356-024-34919-x. Epub 2024 Sep 11. PMID: 39259329. 17: Jiang W, Liu Y, Ke Z, Zhang L, Zhang M, Zhou Y, Wang H, Wu C, Qiu J, Hong Q. Substrate preference of carbamate hydrolase CehA reveals its environmental behavior. J Hazard Mater. 2021 Feb 5;403:123677. doi: 10.1016/j.jhazmat.2020.123677. Epub 2020 Aug 12. PMID: 32835992. 18: Cambon C, Fernandez Y, Falzon M, Mitjavila S. Variations of the digestive absorption kinetics of carbaryl with the nature of the vehicle. Toxicology. 1981;22(1):45-51. doi: 10.1016/0300-483x(81)90006-8. PMID: 6801818. 19: Thi HP, Chu TTH, Nguyen MV. Improved photocatalytic decomposition of carbaryl pesticide in wastewater using ZnO nanorods. J Environ Sci Health B. 2024;59(12):758-766. doi: 10.1080/03601234.2024.2424088. Epub 2024 Nov 11. PMID: 39526484. 20: Flynn K, Kadlec S, Kurker V, Etterson M. Effects of a 28-day early life stage exposure to carbaryl on fathead minnow long-term growth and reproduction. Aquat Toxicol. 2022 Jan;242:106018. doi: 10.1016/j.aquatox.2021.106018. Epub 2021 Nov 8. PMID: 34814091; PMCID: PMC9134262.