MedKoo Cat#: 128921 | Name: PI3K/Akt/mTOR-IN-2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PI3K/Akt/mTOR-IN-2 is a PI3K/AKT/mTOR pathway inhibitor.

Chemical Structure

PI3K/Akt/mTOR-IN-2
PI3K/Akt/mTOR-IN-2
CAS#2757804-89-8

Theoretical Analysis

MedKoo Cat#: 128921

Name: PI3K/Akt/mTOR-IN-2

CAS#: 2757804-89-8

Chemical Formula: C17H13F2NO

Exact Mass: 285.0965

Molecular Weight: 285.29

Elemental Analysis: C, 71.57; H, 4.59; F, 13.32; N, 4.91; O, 5.61

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
PI3K/Akt/mTOR-IN-2; PI3K-Akt/mTOR-IN-2
IUPAC/Chemical Name
1-(3,5-difluorophenyl)-1,3,4,9-tetrahydropyrano[3,4-b]indole
InChi Key
XBYJYKHTEFYLFX-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H13F2NO/c18-11-7-10(8-12(19)9-11)17-16-14(5-6-21-17)13-3-1-2-4-15(13)20-16/h1-4,7-9,17,20H,5-6H2
SMILES Code
FC1=CC(F)=CC(C2OCCC3=C2NC4=C3C=CC=C4)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 285.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L. Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway. Bioorg Med Chem. 2022 Feb 1;55:116594. doi: 10.1016/j.bmc.2021.116594. Epub 2021 Dec 31. PMID: 34990979.