C 410 | CAS#22002-96-6

MedKoo Cat#: 534975 | Name: C 410

Description:

WARNING: This product is for research use only, not for human or veterinary use.

C 410 is a bioactive chemical.

Chemical Structure

C 410

CAS#22002-96-6

Theoretical Analysis

MedKoo Cat#: 534975

Name: C 410

CAS#: 22002-96-6

Chemical Formula: C20H24N4O2

Exact Mass: 352.1899

Molecular Weight: 352.44

Elemental Analysis: C, 68.16; H, 6.86; N, 15.90; O, 9.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

C 410; C-410; C410

IUPAC/Chemical Name

N,N-Diethyl-N'-(1-nitro-9-acridinyl)-1,3-propanediamine

InChi Key

MLPKZUBKJDQRIK-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H24N4O2/c1-3-23(4-2)14-8-13-21-20-15-9-5-6-10-16(15)22-17-11-7-12-18(19(17)20)24(25)26/h5-7,9-12H,3-4,8,13-14H2,1-2H3,(H,21,22)

SMILES Code

O=[N+](C1=CC=CC2=NC3=CC=CC=C3C(NCCCN(CC)CC)=C21)[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 352.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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PMID: 31165412; PMCID: PMC6717603. 4: Marik PE. Is intravenous vitamin C contraindicated in patients with G6PD deficiency? Crit Care. 2019 Apr 3;23(1):109. doi: 10.1186/s13054-019-2397-6. PMID: 30944032; PMCID: PMC6448313. 5: Ge H, Yan Z, Zhu H, Zhao H. MiR-410 exerts neuroprotective effects in a cellular model of Parkinson's disease induced by 6-hydroxydopamine via inhibiting the PTEN/AKT/mTOR signaling pathway. Exp Mol Pathol. 2019 Aug;109:16-24. doi: 10.1016/j.yexmp.2019.05.002. Epub 2019 May 5. PMID: 31067440. 6: Wen R, Umeano AC, Essegian DJ, Sabitaliyevich UY, Wang K, Farooqi AA. Role of microRNA-410 in molecular oncology: A double edged sword. J Cell Biochem. 2018 Nov;119(11):8737-8742. doi: 10.1002/jcb.27251. Epub 2018 Aug 7. PMID: 30086210. 7: Marik PE, Payen D. CITRIS-ALI: How statistics were used to obfuscate the true findings. Anaesth Crit Care Pain Med. 2019 Dec;38(6):575-577. doi: 10.1016/j.accpm.2019.10.004. PMID: 31785700. 8: Yang N, Chen J, Zhang H, Wang X, Yao H, Peng Y, Zhang W. LncRNA OIP5-AS1 loss-induced microRNA-410 accumulation regulates cell proliferation and apoptosis by targeting KLF10 via activating PTEN/PI3K/AKT pathway in multiple myeloma. Cell Death Dis. 2017 Aug 10;8(8):e2975. doi: 10.1038/cddis.2017.358. PMID: 28796257; PMCID: PMC5596549. 9: Sun WL, Kang T, Wang YY, Sun JP, Li C, Liu HJ, Yang Y, Jiao BH. Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410. Biosci Rep. 2019 Jan 3;39(1):BSR20180395. doi: 10.1042/BSR20180395. PMID: 30498093; PMCID: PMC6328889. 10: Marik PE. Procalcitonin is an essential biomarker for hydrocortisone, ascorbic acid, and thiamine (HAT) therapy in patients with sepsis. Crit Care. 2019 May 2;23(1):151. doi: 10.1186/s13054-019-2445-2. PMID: 31046800; PMCID: PMC6498640. 11: Marik PE, Hooper MH. Adjuvant Vitamin C in critically ill patients undergoing renal replacement therapy: What's the right dose? Crit Care. 2018 Nov 22;22(1):320. doi: 10.1186/s13054-018-2190-y. PMID: 30466487; PMCID: PMC6249758. 12: Hooper MH, Carr A, Marik PE. The adrenal-vitamin C axis: from fish to guinea pigs and primates. Crit Care. 2019 Jan 28;23(1):29. doi: 10.1186/s13054-019-2332-x. PMID: 30691525; PMCID: PMC6348603. 13: Geist J, Kontrogianni-Konstantopoulos A. MYBPC1, an Emerging Myopathic Gene: What We Know and What We Need to Learn. Front Physiol. 2016 Sep 14;7:410. doi: 10.3389/fphys.2016.00410. PMID: 27683561; PMCID: PMC5021714. 14: Yang F, Li T, Dong Z, Mi R. MicroRNA-410 is involved in mitophagy after cardiac ischemia/reperfusion injury by targeting high-mobility group box 1 protein. J Cell Biochem. 2018 Feb;119(2):2427-2439. doi: 10.1002/jcb.26405. Epub 2017 Nov 16. PMID: 28914970. 15: Qi HX, Cao Q, Sun XZ, Zhou W, Hong Z, Hu J, -X Juan C, Li S, Kuai WX. MiR-410 regulates malignant biological behavior of pediatric acute lymphoblastic leukemia through targeting FKBP5 and Akt signaling pathway. Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8797-8804. doi: 10.26355/eurrev_201812_16647. PMID: 30575921. 16: Liu Y, Gao Y, Li D, Fleming J, Li H, Bi L. Crystal structure of Rv3899c(184-410), a hypothetical protein from Mycobacterium tuberculosis. Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):642-5. doi: 10.1107/S2053230X16010943. Epub 2016 Jul 27. PMID: 27487929; PMCID: PMC4973306. 17: Thirumoorthy K, Karton A, Thimmakondu VS. From High-Energy C7H2 Isomers with A Planar Tetracoordinate Carbon Atom to An Experimentally Known Carbene. J Phys Chem A. 2018 Nov 21;122(46):9054-9064. doi: 10.1021/acs.jpca.8b08809. Epub 2018 Nov 7. PMID: 30365332. 18: Liu D, Zhang N, Zhang J, Zhao H, Wang X. miR-410 suppresses the expression of interleukin-6 as well as renal fibrosis in the pathogenesis of lupus nephritis. Clin Exp Pharmacol Physiol. 2016 Jun;43(6):616-25. doi: 10.1111/1440-1681.12576. PMID: 27028192. 19: Luo X, Wu Y, Liu T, Li F, Li X, Chen D, Wang Y. Quantifying Redox Dynamics of c-Type Cytochromes in a Living Cell Suspension of Dissimilatory Metal- reducing Bacteria. Anal Sci. 2019 Mar 10;35(3):315-321. doi: 10.2116/analsci.18P394. Epub 2018 Nov 16. PMID: 30449834. 20: Ke X, Yuan Y, Guo C, Yang Y, Pu Q, Hu X, Tang K, Luo X, Jiang Q, Su X, Liu L, Zhu W, Wei Y. MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer. Oncotarget. 2017 Feb 14;8(7):11356-11371. doi: 10.18632/oncotarget.14529. PMID: 28076327; PMCID: PMC5355270.