MedKoo Cat#: 128916 | Name: PJN31586
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PJN31586, also named as N6-Methyl-dA Phosphoramidite, is a nucleoside building block that has been used in the synthesis of hemimethylated oligonucleotides.

Chemical Structure

PJN31586
PJN31586
CAS#105931-58-6

Theoretical Analysis

MedKoo Cat#: 128916

Name: PJN31586

CAS#: 105931-58-6

Chemical Formula: C41H50N7O6P

Exact Mass: 767.3560

Molecular Weight: 767.87

Elemental Analysis: C, 64.13; H, 6.56; N, 12.77; O, 12.50; P, 4.03

Price and Availability

Size Price Availability Quantity
50mg USD 350.00 2 Weeks
100mg USD 550.00 2 Weeks
250mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
N6-Methyl-dA Phosphoramidite; PJN31586
IUPAC/Chemical Name
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChi Key
PTWRBAYAPDVZGR-JNTXQERPSA-N
InChi Code
InChI=1S/C41H50N7O6P/c1-28(2)48(29(3)4)55(52-23-11-22-42)54-35-24-37(47-27-46-38-39(43-5)44-26-45-40(38)47)53-36(35)25-51-41(30-12-9-8-10-13-30,31-14-18-33(49-6)19-15-31)32-16-20-34(50-7)21-17-32/h8-10,12-21,26-29,35-37H,11,23-25H2,1-7H3,(H,43,44,45)/t35-,36+,37+,55?/m0/s1
SMILES Code
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C6=NC=NC(NC)=C6N=C5)C[C@@H]4OP(OCCC#N)N(C(C)C)C(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 767.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Ishikawa, K., Handa, N., and Kobayashi, I. Cleavage of a model DNA replication fork by a Type I restriction endonuclease. Nucleic Acids Res. 37(11), 3531-3544 (2009).