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MedKoo Cat#: 577233 | Name: Meteneprost potassium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Meteneprost potassium is a compound used as an early pregnancy terminator. It is a derivative of both PGE2 & PGF2alpha.

Chemical Structure

Meteneprost potassium
CAS#122576-55-0

Theoretical Analysis

MedKoo Cat#: 577233

Name: Meteneprost potassium

CAS#: 122576-55-0

Chemical Formula: C23H37KO4

Exact Mass: 416.2329

Molecular Weight: 416.64

Elemental Analysis: C, 66.30; H, 8.95; K, 9.38; O, 15.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Meteneprost potassium
IUPAC/Chemical Name
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, monopotassium salt, (5Z,11alpha,13E,15R)-
InChi Key
AWJFDDHQLBRQDS-PWOMVKEHSA-M
InChi Code
InChI=1S/C23H38O4.K/c1-5-6-15-23(3,4)21(25)14-13-19-18(17(2)16-20(19)24)11-9-7-8-10-12-22(26)27;/h7,9,13-14,18-21,24-25H,2,5-6,8,10-12,15-16H2,1,3-4H3,(H,26,27);/q;+1/p-1/b9-7-,14-13+;/t18-,19+,20+,21+;/m0./s1
SMILES Code
[K+].CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=C)[C@@H]1C\C=C/CCCC(=O)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: A multicentre randomized comparative clinical trial of 200 mg RU486 (mifepristone) single dose followed by either 5 mg 9-methylene PGE(2) gel (meteneprost) or 600 microg oral PGE(1) (misoprostol) for termination of early pregnancy within 28 days of missed menstrual period. ICMR Task Force Study. Indian Council of Medical Research. Contraception. 2000 Sep;62(3):125-30. PubMed PMID: 11124359. 2: Kimball FA, Cornette JC, Bundy GL, Kirton KT. Plasma concentrations of 9-deoxo-16-dimethyl-9-methylene-PGE2 in rhesus monkeys after administration by various routes. Prostaglandins. 1980 Sep;20(3):559-69. PubMed PMID: 7422900. 3: Shapiro AG, Lasseter K, Cobiella A, Domenzain M. Intravaginal administration of 9-deoxo-9-methylene-16,16-dimethyl PGE2 for cervical dilation prior to suction curettage. Int J Gynaecol Obstet. 1982 Apr;20(2):137-40. PubMed PMID: 6125434. 4: Brenner PF, Marrs RP, Roy S, Mishell DR Jr. Termination of early gestation with 9-deoxo-16,16-dimethyl-9-methylene prostaglandin E2. Contraception. 1982 Sep;26(3):261-77. PubMed PMID: 6184197

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