MedKoo Cat#: 128915 | Name: Lipid 35 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lipid 35 is an ionizable cationic lipid (pKa = 7.6) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.

Chemical Structure

Lipid 35 HCl
Lipid 35 HCl
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128915

Name: Lipid 35 HCl

CAS#: N/A

Chemical Formula: C56H116Cl4N4O5

Exact Mass: 1064.7700

Molecular Weight: 1067.37

Elemental Analysis: C, 63.02; H, 10.95; Cl, 13.29; N, 5.25; O, 7.49

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
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Related CAS #
No Data
Synonym
Lipid 35 HCl; Lipid-35 HCl; Lipid-35; Lipid 35 hydrochloride
IUPAC/Chemical Name
11-(8-((2-hexyldecanoyl)oxy)octyl)-2-methyl-7-oxo-2,6,8,11-tetraazanonadecan-19-yl 2-hexyldecanoate tetrahydrochloride
InChi Key
XGGBNRJTIIBMND-UHFFFAOYSA-N
InChi Code
InChI=1S/C56H112N4O5.4ClH/c1-7-11-15-19-25-33-42-52(40-31-17-13-9-3)54(61)64-50-37-29-23-21-27-35-47-60(49-45-58-56(63)57-44-39-46-59(5)6)48-36-28-22-24-30-38-51-65-55(62)53(41-32-18-14-10-4)43-34-26-20-16-12-8-2;;;;/h52-53H,7-51H2,1-6H3,(H2,57,58,63);4*1H
SMILES Code
CCCCCCCCC(CCCCCC)C(OCCCCCCCCN(CCCCCCCCOC(C(CCCCCC)CCCCCCCC)=O)CCNC(NCCCN(C)C)=O)=O.Cl.Cl.Cl.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,067.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Naidu, G.S., Rampado, R., Sharma, P., et al. Ionizable lipids with optimized linkers enable lung-specific, lipid nanoparticle-mediated mRNA delivery for treatment of metastatic lung tumors. ACS Nano 19(6), 6571-6587 (2025).