MedKoo Cat#: 341384 | Name: Vamicamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Vamicamide is a biochemical.

Chemical Structure

Vamicamide
Vamicamide
CAS#132373-81-0

Theoretical Analysis

MedKoo Cat#: 341384

Name: Vamicamide

CAS#: 132373-81-0

Chemical Formula: C18H23N3O

Exact Mass: 297.1841

Molecular Weight: 297.40

Elemental Analysis: C, 72.70; H, 7.80; N, 14.13; O, 5.38

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Vamicamide;
IUPAC/Chemical Name
2-Pyridineacetamide, alpha-(2-(dimethylamino)propyl)-alpha-phenyl-, (R*,R*)-(+-)-
InChi Key
BWNLUIXQIHPUGO-RDTXWAMCSA-N
InChi Code
InChI=1S/C18H23N3O/c1-14(21(2)3)13-18(17(19)22,15-9-5-4-6-10-15)16-11-7-8-12-20-16/h4-12,14H,13H2,1-3H3,(H2,19,22)/t14-,18-/m1/s1
SMILES Code
c1(ccccn1)[C@](C(N)=O)(c1ccccc1)C[C@H](N(C)C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 297.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cadranel JF, Boujenah JL, Bourlière M, Fontanges T, Pol S, Trepo C, Ouzan D. Satisfaction of patients treated for chronic hepatitis C with the peginterferon alfa-2b pen device: the VISA observational study. Gastroenterol Clin Biol. 2007 Feb;31(2):180-4. PubMed PMID: 17347628. 2: Yono M, Yoshida M, Takahashi W, Inadome A, Ueda S. Comparison of the effects of novel antimuscarinic drugs on human detrusor smooth muscle. BJU Int. 2000 Oct;86(6):719-25. PubMed PMID: 11069384. 3: Yamamoto T, Honbo T, Tokoro K, Kojimoto Y, Kodama R, Ohtsuka M, Shimomura K. General pharmacology of the new antimuscarinic compound vamicamide. Arzneimittelforschung. 1995 Dec;45(12):1274-84. PubMed PMID: 8595084. 4: Yamamoto T, Koibuchi Y, Miura S, Sawada T, Ozaki R, Esumi K, Ohtsuka M. Effects of vamicamide on urinary bladder functions in conscious dog and rat models of urinary frequency. J Urol. 1995 Dec;154(6):2174-8. PubMed PMID: 7500484. 5: Oyasu H, Nakanishi I, Tanaka A, Murano K, Matsuo M. Conformational studies on the four stereoisomers of the novel anticholinergic 4-(dimethylamino)-2-phenyl-2-(2-pyridyl)pentanamide. J Comput Aided Mol Des. 1995 Apr;9(2):171-80. PubMed PMID: 7608748. 6: Oyasu H, Yamamoto T, Sato N, Sawada T, Ozaki R, Mukai T, Ozaki T, Nishii M, Sato H, Fujiwara T, et al. Urinary bladder-selective action of the new antimuscarinic compound vamicamide. Arzneimittelforschung. 1994 Nov;44(11):1242-9. PubMed PMID: 7848339. 7: Oyasu H, Nagano M, Akahane A, Tomoi M, Tada T, Matsuo M. Synthesis and anticholinergic activity of the four stereoisomers of 4-(dimethylamino)-2-phenyl-2-(2-pyridyl)pentanamide. J Med Chem. 1994 Apr 29;37(9):1378-81. PubMed PMID: 8176715. 8: Suzuki A, Takagaki S, Suzuki H, Noda K. Determination of the R,R- and S,S-enantiomers of vamicamide in human serum and urine by high-performance liquid chromatography on a Chiral-AGP column. J Chromatogr. 1993 Aug 11;617(2):279-84. PubMed PMID: 8408394.