MedKoo Cat#: 128895 | Name: DOPE-C8
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DOPE-C8 is a zwitterionic glycerophospholipid that has been used in the generation of lipid nanoparticles (LNPs) for mRNA delivery in vivo.

Chemical Structure

DOPE-C8
DOPE-C8
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128895

Name: DOPE-C8

CAS#: N/A

Chemical Formula: C52H98NO10P

Exact Mass: 927.6928

Molecular Weight: 928.33

Elemental Analysis: C, 67.28; H, 10.64; N, 1.51; O, 17.23; P, 3.34

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 1,050.00 2 Weeks
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Related CAS #
No Data
Synonym
DOPE-C8; 1,2-DOPE-C8
IUPAC/Chemical Name
(R)-2,3-bis(oleoyloxy)propyl (2-((3-(octyloxy)-3-oxopropyl)ammonio)ethyl) phosphate
InChi Key
LMYALPDFFQOFKR-ZYMZSVROSA-N
InChi Code
InChI=1S/C52H98NO10P/c1-4-7-10-13-16-18-20-22-24-26-28-30-32-34-37-40-50(54)60-47-49(63-52(56)41-38-35-33-31-29-27-25-23-21-19-17-14-11-8-5-2)48-62-64(57,58)61-46-44-53-43-42-51(55)59-45-39-36-15-12-9-6-3/h22-25,49,53H,4-21,26-48H2,1-3H3,(H,57,58)/b24-22-,25-23-/t49-/m1/s1
SMILES Code
CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCC[NH2+]CCC(OCCCCCCCC)=O)([O-])=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 928.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL