MedKoo Cat#: 128881 | Name: 5-Hydroxypropafenone HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

5-Hydroxypropafenone is an active metabolite of propafenone.

Chemical Structure

5-Hydroxypropafenone HCl
5-Hydroxypropafenone HCl
CAS#86383-32-6

Theoretical Analysis

MedKoo Cat#: 128881

Name: 5-Hydroxypropafenone HCl

CAS#: 86383-32-6

Chemical Formula: C21H28ClNO4

Exact Mass: 393.1707

Molecular Weight: 393.91

Elemental Analysis: C, 64.03; H, 7.17; Cl, 9.00; N, 3.56; O, 16.25

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
5-Hydroxypropafenone (hydrochloride); 5-Hydroxypropafenone; Lu 40545
IUPAC/Chemical Name
1-(5-hydroxy-2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
InChi Key
FAYLNKVZLXBDBE-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H27NO4.ClH/c1-2-12-22-14-18(24)15-26-21-11-9-17(23)13-19(21)20(25)10-8-16-6-4-3-5-7-16;/h3-7,9,11,13,18,22-24H,2,8,10,12,14-15H2,1H3;1H
SMILES Code
O=C(CCC1=CC=CC=C1)C2=CC(O)=CC=C2OCC(O)CNCCC.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 393.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Cahill, S.A., Kirshenbaum, L.A., and Gross, G.J. Transient outward current inhibition by propafenone and 5-hydroxypropafenone in cultured neonatal rat ventricular myocytes. J. Cardiovasc. Pharmacol. 38(3), 460-467 (2001). 2. Boucher, M., Chassaing, C., Hamel, J.D., et al. Cardiac electrophysiological effects of propafenone and its 5-hydroxylated metabolite in the conscious dog. Eur. J. Pharmacol. 314(2), 171-177 (1996).