Brosalpramide is a dopamine D2 receptor antagonist primarily investigated for its prokinetic and antiemetic properties. It enhances gastrointestinal motility by blocking D2 receptors in the gastrointestinal tract and central nervous system, promoting acetylcholine release. This mechanism helps alleviate symptoms like nausea, vomiting, and gastric stasis.
MedKoo Cat#: 146331
Name: Brosalpramide
CAS#: 7771-03-1
Chemical Formula: C10H12BrNO2
Exact Mass: 257.0051
Molecular Weight: 258.12
Elemental Analysis: C, 46.53; H, 4.69; Br, 30.96; N, 5.43; O, 12.40
The following data is based on the product molecular weight 258.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |