MedKoo Cat#: 128869 | Name: ALKS-2680

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ALKS-2680 is an OX2 agonist.

Chemical Structure

ALKS-2680
ALKS-2680
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128869

Name: ALKS-2680

CAS#: N/A

Chemical Formula: C21H30N2O5S

Exact Mass: 422.1875

Molecular Weight: 422.54

Elemental Analysis: C, 59.69; H, 7.16; N, 6.63; O, 18.93; S, 7.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ALKS-2680; ALKS2680; ALKS 2680
IUPAC/Chemical Name
N-((21S,24S,52R,53S)-6-oxo-3,8-dioxa-5(2,1)-piperidina-1(1,2)-benzena-2(1,4)-cyclohexanacyclooctaphane-53-yl)methanesulfonamide
InChi Key
IHNJMACFBQEKRJ-NBMJBFSESA-N
InChi Code
InChI=1S/C21H30N2O5S/c1-29(25,26)22-18-6-4-12-23-19(18)13-27-16-10-8-15(9-11-16)17-5-2-3-7-20(17)28-14-21(23)24/h2-3,5,7,15-16,18-19,22H,4,6,8-14H2,1H3/t15-,16+,18-,19-/m0/s1
SMILES Code
O=C1COC2=CC=CC=C2[C@H]3CC[C@@H](OC[C@H]4[C@@H](NS(=O)(C)=O)CCCN14)CC3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 422.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Yee B, Chapman J, Grunstein R, Argent C, D’Rozario A, Hopkinson C, Ramos J, Landry I, Yagoda S, Rege B. O013 Preliminary Results from a Phase 1 Study of ALKS 2680, an Orexin-2 receptor Agonist, in Healthy Participants and Patients with Narcolepsy or Idiopathic Hypersomnia. Sleep Adv. 2023 Oct 23;4(Suppl 1):A5–6. doi: 10.1093/sleepadvances/zpad035.013. PMCID: PMC10591782.