MedKoo Cat#: 128860 | Name: QQN46637
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

QQN46637, also named as 5'-DMT-5-F-2'-dU Phosphoramidite, is a nucleoside building block.

Chemical Structure

QQN46637
QQN46637
CAS#142246-63-7

Theoretical Analysis

MedKoo Cat#: 128860

Name: QQN46637

CAS#: 142246-63-7

Chemical Formula: C39H46FN4O8P

Exact Mass: 748.3037

Molecular Weight: 748.79

Elemental Analysis: C, 62.56; H, 6.19; F, 2.54; N, 7.48; O, 17.09; P, 4.14

Price and Availability

Size Price Availability Quantity
25mg USD 350.00 2 Weeks
50mg USD 650.00 2 Weeks
100mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
5'-DMT-5-F-2'-dU Phosphoramidite; QQN46637
IUPAC/Chemical Name
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChi Key
QXDBDJDCIBKCKF-QMTPQUJBSA-N
InChi Code
InChI=1S/C39H46FN4O8P/c1-26(2)44(27(3)4)53(50-22-10-21-41)52-34-23-36(43-24-33(40)37(45)42-38(43)46)51-35(34)25-49-39(28-11-8-7-9-12-28,29-13-17-31(47-5)18-14-29)30-15-19-32(48-6)20-16-30/h7-9,11-20,24,26-27,34-36H,10,22-23,25H2,1-6H3,(H,42,45,46)/t34-,35+,36+,53?/m0/s1
SMILES Code
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C(NC(C(F)=C5)=O)=O)C[C@@H]4OP(OCCC#N)N(C(C)C)C(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 748.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Mou, Q., Ma, Y., Pan, G., et al. DNA trojan horses: Self-assembled floxuridine-containing DNA polyhedra for cancer therapy. Angew Chem. Int. Ed. Engl. 56(41), 12528-12532 (2017).