MedKoo Cat#: 146300 | Name: Pyributicarb

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyributicarb is a pre-emergent carbamate herbicide used primarily to control annual grasses and broadleaf weeds in crops such as rice. It works by inhibiting cell division in germinating weed seeds, disrupting microtubule formation and interfering with normal plant development. The herbicide is absorbed mainly through the shoots of emerging seedlings and exhibits selectivity that protects the crop. Its application helps maintain crop yields by reducing early weed competition.

Chemical Structure

Pyributicarb
Pyributicarb
CAS#88678-67-5

Theoretical Analysis

MedKoo Cat#: 146300

Name: Pyributicarb

CAS#: 88678-67-5

Chemical Formula: C18H22N2O2S

Exact Mass: 330.1402

Molecular Weight: 330.45

Elemental Analysis: C, 65.43; H, 6.71; N, 8.48; O, 9.68; S, 9.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Pyributicarb;
IUPAC/Chemical Name
O-(3-(tert-butyl)phenyl) (6-methoxypyridin-2-yl)(methyl)carbamothioate
InChi Key
VTRWMTJQBQJKQH-UHFFFAOYSA-N
InChi Code
1S/C18H22N2O2S/c1-18(2,3)13-8-6-9-14(12-13)22-17(23)20(4)15-10-7-11-16(19-15)21-5/h6-12H,1-5H3
SMILES Code
COC1=CC=CC(=N1)N(C)C(=S)OC2=CC=CC(=C2)C(C)(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 330.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sun X, Zhang W, Huang T, He Y, Li H, Su P, Yang Y. Purity determination of pyributicarb by internal standard correction-high-performance liquid chromatography-quantitative nuclear magnetic resonance. Anal Bioanal Chem. 2020 Oct;412(25):6983-6993. doi: 10.1007/s00216-020-02832-0. Epub 2020 Aug 4. PMID: 32754793. 2: Matsubara T, Noracharttiyapot W, Toriyabe T, Yoshinari K, Nagata K, Yamazoe Y. Assessment of human pregnane X receptor involvement in pesticide-mediated activation of CYP3A4 gene. Drug Metab Dispos. 2007 May;35(5):728-33. doi: 10.1124/dmd.106.013144. Epub 2007 Feb 9. PMID: 17293382. 3: Hirose S, Kawahigashi H, Ozawa K, Shiota N, Inui H, Ohkawa H, Ohkawa Y. Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides. J Agric Food Chem. 2005 May 4;53(9):3461-7. doi: 10.1021/jf050064z. PMID: 15853388. 4: Kojima H, Sata F, Takeuchi S, Sueyoshi T, Nagai T. Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. Toxicology. 2011 Feb 27;280(3):77-87. doi: 10.1016/j.tox.2010.11.008. Epub 2010 Nov 27. PMID: 21115097. 5: Ninomiya K, Oogami Y, Kino-Oka M, Taya M. Elongating responses to herbicides of heterotrophic and photoautotrophic hairy roots derived from pak-bung plant. J Biosci Bioeng. 2002;93(5):505-8. doi: 10.1016/s1389-1723(02)80100-1. PMID: 16233240. 6: Tsuda T, Nakamura T, Inoue A, Tanaka K. Pesticides in water, fish and shellfish from littoral area of Lake Biwa. Bull Environ Contam Toxicol. 2009 Jun;82(6):716-21. doi: 10.1007/s00128-009-9681-0. Epub 2009 Mar 10. PMID: 19277442. 7: Ninomiya K, Tsushima Y, King-Oka M, Taya M. An automatic image analyzing system for evaluation of elongating behavior of plant hairy roots exposed to herbicidal stimuli. J Biosci Bioeng. 2003;96(1):98-101. PMID: 16233493.