MedKoo Cat#: 128729 | Name: Cbz-Gly-Pro-Arg-pNA (acetate)
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cbz-Gly-Pro-Arg-pNA is a colorimetric substrate for proteases, including thrombin and mast cell tryptase.

Chemical Structure

Cbz-Gly-Pro-Arg-pNA (acetate)
Cbz-Gly-Pro-Arg-pNA (acetate)
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128729

Name: Cbz-Gly-Pro-Arg-pNA (acetate)

CAS#: N/A

Chemical Formula: C29H38N8O9

Exact Mass: 0.0000

Molecular Weight: 642.67

Elemental Analysis: C, 54.20; H, 5.96; N, 17.44; O, 22.41

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Cbz-Gly-Pro-Arg-pNA; Cbz-GPR-pNA; Cbz-GPR-p-nitroanilide Protease; Chromogenic Substrate
IUPAC/Chemical Name
benzyl (2-((S)-2-(((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)carbamate acetate
InChi Key
FPMAXHHYPVIJMC-VROPFNGYSA-N
InChi Code
InChI=1S/C27H34N8O7.C2H4O2/c28-26(29)30-14-4-8-21(24(37)32-19-10-12-20(13-11-19)35(40)41)33-25(38)22-9-5-15-34(22)23(36)16-31-27(39)42-17-18-6-2-1-3-7-18;1-2(3)4/h1-3,6-7,10-13,21-22H,4-5,8-9,14-17H2,(H,31,39)(H,32,37)(H,33,38)(H4,28,29,30);1H3,(H,3,4)/t21-,22-;/m0./s1
SMILES Code
O=C([C@@H]1CCCN1C(CNC(OCC2=CC=CC=C2)=O)=O)N[C@H](C(NC3=CC=C(C=C3)[N+]([O-])=O)=O)CCCNC(N)=N.CC(O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 642.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Hogg, P.J., and Jackson, C.M. Formation of a ternary complex between thrombin, fibrin monomer, and heparin influences the action of thrombin on its substrates. The Journal of Biological Chemisty 265(1), 248-255 (1990). 2. Harvima, I.T., Harvima, R.J., Eloranta, T.O., et al. The allosteric effect of salt on human mast cell tryptase. Biochim. Biophys. Acta 956(2), 133-139 (1988).