MedKoo Cat#: 128717 | Name: Lipid TG4C
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lipid TG4C is an ionizable cationic glycerolipid (pKa = 6.71) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.

Chemical Structure

Lipid TG4C
Lipid TG4C
CAS#3028336-07-1

Theoretical Analysis

MedKoo Cat#: 128717

Name: Lipid TG4C

CAS#: 3028336-07-1

Chemical Formula: C55H103NO10

Exact Mass: 937.7582

Molecular Weight: 938.43

Elemental Analysis: C, 70.40; H, 11.06; N, 1.49; O, 17.05

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 750.00 2 Weeks
10mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
Lipid TG4C; LipidTG4C; Lipid-TG4C;
IUPAC/Chemical Name
O,O'-(2-((4-(dimethylamino)butanoyl)oxy)propane-1,3-diyl) di(heptadecan-9-yl) diadipate
InChi Key
CNJVKTXUIDKKIW-UHFFFAOYSA-N
InChi Code
InChI=1S/C55H103NO10/c1-7-11-15-19-23-27-36-48(37-28-24-20-16-12-8-2)64-53(59)42-33-31-40-51(57)62-46-50(66-55(61)44-35-45-56(5)6)47-63-52(58)41-32-34-43-54(60)65-49(38-29-25-21-17-13-9-3)39-30-26-22-18-14-10-4/h48-50H,7-47H2,1-6H3
SMILES Code
CN(C)CCCC(OC(COC(CCCCC(OC(CCCCCCCC)CCCCCCCC)=O)=O)COC(CCCCC(OC(CCCCCCCC)CCCCCCCC)=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 938.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Huang, K., Liu, Y., Miao, H., et al. Nebulized lipid nanoparticles based on degradable ionizable glycerolipid for potent pulmonary mRNA delivery. ACS Nano 19(1), 1128-1139 (2025).