MedKoo Cat#: 128700 | Name: A28-C6B2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

A28-C6B2 is an ionizable cationic lipid (pKa = 6.43) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.

Chemical Structure

A28-C6B2
A28-C6B2
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128700

Name: A28-C6B2

CAS#: N/A

Chemical Formula: C41H81NO5

Exact Mass: 667.6115

Molecular Weight: 668.10

Elemental Analysis: C, 73.71; H, 12.22; N, 2.10; O, 11.97

Price and Availability

Size Price Availability Quantity
1mg USD 450.00 2 Weeks
5mg USD 950.00 2 Weeks
10mg USD 1,550.00 2 Weeks
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Related CAS #
No Data
Synonym
A28-C6B2; A28 C6B2; A28C6B2
IUPAC/Chemical Name
bis(2-butyloctyl) 6,6'-((5-hydroxypentyl)azanediyl)dihexanoate
InChi Key
LRSNKXRFKNSFSY-UHFFFAOYSA-N
InChi Code
InChI=1S/C41H81NO5/c1-5-9-13-18-28-38(26-11-7-3)36-46-40(44)30-20-15-22-32-42(34-24-17-25-35-43)33-23-16-21-31-41(45)47-37-39(27-12-8-4)29-19-14-10-6-2/h38-39,43H,5-37H2,1-4H3
SMILES Code
CCCCCCC(CCCC)COC(CCCCCN(CCCCCO)CCCCCC(OCC(CCCCCC)CCCC)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 668.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Ren, Y., Zeng, L., Tang, Y., et al. Enhancing spleen-targeted mRNA delivery with branched biodegradable tails in lipid nanoparticles. J. Mater. Chem. B. 12(33), 8062-8066 (2024).