MedKoo Cat#: 146095 | Name: Valsarin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Valsarin is a pharmacological agent that primarily acts as an angiotensin II receptor antagonist, blocking the effects of angiotensin II on its receptors and thereby helping to regulate blood pressure. By inhibiting this receptor, Valsarin helps to relax blood vessels, reduce fluid retention, and decrease overall blood pressure. It is commonly used in the treatment of hypertension and heart failure, as well as in reducing the risk of stroke and kidney complications in patients with diabetes.

Chemical Structure

Valsarin
Valsarin
CAS#22851-88-3

Theoretical Analysis

MedKoo Cat#: 146095

Name: Valsarin

CAS#: 22851-88-3

Chemical Formula: C15H9ClO6

Exact Mass: 320.0088

Molecular Weight: 320.68

Elemental Analysis: C, 56.18; H, 2.83; Cl, 11.05; O, 29.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Valsarin; Papulosin;
IUPAC/Chemical Name
3-chloro-1,2,4,5-tetrahydroxy-7-methylanthracene-9,10-dione
InChi Key
LSXDSQPJNKGFHK-UHFFFAOYSA-N
InChi Code
1S/C15H9ClO6/c1-4-2-5-7(6(17)3-4)12(19)9-8(11(5)18)14(21)15(22)10(16)13(9)20/h2-3,17,20-22H,1H3
SMILES Code
CC1=CC(O)=C2C(=O)C3=C(C(O)=C(O)C(Cl)=C3O)C(=O)C2=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 320.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lam JK, Sargent MV, Elix JA, Smith DO. Synthesis of valsarin and 5,7-dichloroemodin. J Chem Soc Perkin 1. 1972;12:1466-70. doi: 10.1039/p19720001466. PMID: 5065336. 2: Briggs LH, Castaing DR, Denyer AN, Orgias EF, Small CW. Chemistry of fungi. 8. Constituents of Valsaria rubricosa and the identification of papulosin with valsarin. J Chem Soc Perkin 1. 1972;12:1464-6. doi: 10.1039/p19720001464. PMID: 5065335.