MedKoo Cat#: 127323 | Name: JFB01

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JFB01 is an HDAC inhibitor and a Vitamin D Receptor Agonist.

Chemical Structure

JFB01
JFB01
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127323

Name: JFB01

CAS#: N/A

Chemical Formula: C27H39NO5

Exact Mass: 457.2828

Molecular Weight: 457.61

Elemental Analysis: C, 70.87; H, 8.59; N, 3.06; O, 17.48

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
JFB01; JF-B01; JFB-01
IUPAC/Chemical Name
N-hydroxy-2-(4-(3-(4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)acetamide
InChi Key
HLEDBIQBAUIWNJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H39NO5/c1-8-27(9-2,21-11-13-23(19(4)15-21)33-17-25(30)28-31)20-10-12-22(18(3)14-20)32-16-24(29)26(5,6)7/h10-15,24,29,31H,8-9,16-17H2,1-7H3,(H,28,30)
SMILES Code
ONC(COC1=CC=C(C(CC)(CC)C2=CC(C)=C(OCC(O)C(C)(C)C)C=C2)C=C1C)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 457.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Bijian K, Kaldre D, Wang TT, Su J, Bouttier M, Boucher A, Alaoui-Jamali M, White JH, Gleason JL. Efficacy of hybrid vitamin D receptor agonist/histone deacetylase inhibitors in vitamin D-resistant triple-negative 4T1 breast cancer. J Steroid Biochem Mol Biol. 2018 Mar;177:135-139. doi: 10.1016/j.jsbmb.2017.08.010. Epub 2017 Aug 25. PMID: 28847749.