Ravenelin | CAS#479-44-7 | biochemical

MedKoo Cat#: 146081 | Name: Ravenelin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ravenelin is a naturally occurring compound found in certain plant species, with potential applications in medicinal chemistry. It has been studied for its pharmacological properties, including its possible use as an anticancer and anti-inflammatory agent. The mechanism of ravenelin involves modulating cellular pathways, such as inhibiting the growth of cancer cells and reducing inflammation, possibly through the regulation of specific enzymes or signaling pathways.

Chemical Structure

Ravenelin

CAS#479-44-7

Theoretical Analysis

MedKoo Cat#: 146081

Name: Ravenelin

CAS#: 479-44-7

Chemical Formula: C14H10O5

Exact Mass: 258.0528

Molecular Weight: 258.23

Elemental Analysis: C, 65.12; H, 3.90; O, 30.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Ravenelin;

IUPAC/Chemical Name

1,4,8-trihydroxy-3-methyl-9H-xanthen-9-one

InChi Key

GFYRPPGRPOFGOW-UHFFFAOYSA-N

InChi Code

1S/C14H10O5/c1-6-5-8(16)11-13(18)10-7(15)3-2-4-9(10)19-14(11)12(6)17/h2-5,15-17H,1H3

SMILES Code

CC1=CC(O)=C2C(=O)C3=C(O)C=CC=C3OC2=C1O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 258.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pina JRS, Silva-Silva JV, Carvalho JM, Bitencourt HR, Watanabe LA, Fernandes JMP, Souza GE, Aguiar ACC, Guido RVC, Almeida-Souza F, Calabrese KDS, Marinho PSB, Marinho AMDR. Antiprotozoal and Antibacterial Activity of Ravenelin, a Xanthone Isolated from the Endophytic Fungus Exserohilum rostratum. Molecules. 2021 Jun 2;26(11):3339. doi: 10.3390/molecules26113339. PMID: 34199336; PMCID: PMC8199546. 2: Nale SD, Maiti D, Lee YR. Construction of Highly Functionalized Xanthones via Rh-Catalyzed Cascade C-H Activation/O-Annulation. Org Lett. 2021 Apr 2;23(7):2465-2470. doi: 10.1021/acs.orglett.1c00391. Epub 2021 Mar 10. PMID: 33719464. 3: Koopklang K, Choodej S, Hantanong S, Intayot R, Jungsuttiwong S, Insumran Y, Ngamrojanavanich N, Pudhom K. Anti-Inflammatory Properties of Oxygenated Isocoumarins and Xanthone from Thai Mangrove-Associated Endophytic Fungus Setosphaeria rostrata. Molecules. 2024 Jan 26;29(3):603. doi: 10.3390/molecules29030603. PMID: 38338348; PMCID: PMC10856793. 4: Padhi S, Masi M, Cimmino A, Tuzi A, Jena S, Tayung K, Evidente A. Funiculosone, a substituted dihydroxanthene-1,9-dione with two of its analogues produced by an endolichenic fungus Talaromyces funiculosus and their antimicrobial activity. Phytochemistry. 2019 Jan;157:175-183. doi: 10.1016/j.phytochem.2018.10.031. Epub 2018 Nov 9. PMID: 30419411. 5: Raistrick H, Robinson R, White DE. Studies in the biochemistry of micro- organisms: Ravenelin (3-methyl-1:4:8-trihydroxyxanthone), a new metabolic product of Helminthosporium Ravenelii Curtis and of H. turcicum Passerini. Biochem J. 1936 Aug;30(8):1303-14. doi: 10.1042/bj0301303. PMID: 16746159; PMCID: PMC1263186.