MedKoo Cat#: 577885 | Name: (S,R,S)-AHPC-C8-NH2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S,R,S)-AHPC-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader.

Chemical Structure

(S,R,S)-AHPC-C8-NH2
(S,R,S)-AHPC-C8-NH2
CAS#2341796-79-8

Theoretical Analysis

MedKoo Cat#: 577885

Name: (S,R,S)-AHPC-C8-NH2

CAS#: 2341796-79-8

Chemical Formula: C31H47N5O4S

Exact Mass: 585.3349

Molecular Weight: 585.81

Elemental Analysis: C, 63.56; H, 8.09; N, 11.96; O, 10.92; S, 5.47

Price and Availability

Size Price Availability Quantity
50mg USD 735.00 2 Weeks
100mg USD 1,100.00 2 Weeks
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Related CAS #
No Data
Synonym
(S,R,S)-AHPC-C8-NH2; VH032-C8-NH2
IUPAC/Chemical Name
(2S,4R)-1-((S)-2-(9-aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChi Key
QLJZVMJBYNFUSG-CERRFVOPSA-N
InChi Code
InChI=1S/C31H47N5O4S/c1-21-27(41-20-34-21)23-14-12-22(13-15-23)18-33-29(39)25-17-24(37)19-36(25)30(40)28(31(2,3)4)35-26(38)11-9-7-5-6-8-10-16-32/h12-15,20,24-25,28,37H,5-11,16-19,32H2,1-4H3,(H,33,39)(H,35,38)/t24-,25+,28-/m1/s1
SMILES Code
O=C([C@H]1N(C([C@@H](NC(CCCCCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 585.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL