MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 146075 | Name: Picolinohydrazide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Picolinohydrazide is a chemical compound that functions as a hydrazide derivative, which is often explored in pharmaceutical and chemical research. It has potential applications in the synthesis of biologically active molecules, particularly those with antimicrobial and antitumor properties. The mechanism of picolinohydrazide typically involves the formation of hydrazone bonds with carbonyl compounds, which can affect various biochemical pathways in target organisms or cells. While its direct therapeutic use is not well-established, its applications in drug design and chemical synthesis are of interest in developing novel therapeutic agents.

Chemical Structure

Picolinohydrazide
Picolinohydrazide
CAS#1452-63-7

Theoretical Analysis

MedKoo Cat#: 146075

Name: Picolinohydrazide

CAS#: 1452-63-7

Chemical Formula: C6H7N3O

Exact Mass: 137.0589

Molecular Weight: 137.14

Elemental Analysis: C, 52.55; H, 5.15; N, 30.64; O, 11.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Picolinohydrazide;
IUPAC/Chemical Name
picolinohydrazide
InChi Key
BAQLNPIEFOYKNB-UHFFFAOYSA-N
InChi Code
1S/C6H7N3O/c7-9-6(10)5-3-1-2-4-8-5/h1-4H,7H2,(H,9,10)
SMILES Code
NNC(=O)C1=CC=CC=N1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 137.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Priebe JP, Mello RS, Nome F, Bortoluzzi AJ. Nicotinohydrazide. Acta Crystallogr Sect E Struct Rep Online. 2007 Dec 18;64(Pt 1):o302-3. doi: 10.1107/S160053680706655X. PMID: 21200867; PMCID: PMC2915351. 2: Akkurt M, Khandar AA, Tahir MN, Yazdi SA, Afkhami FA. Dibromido{N'-[1-(pyridin-2-yl)ethyl-idene]picolinohydrazide-κ(2)N',O}cadmium. Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):m842. doi: 10.1107/S1600536812023185. Epub 2012 May 31. PMID: 22719380; PMCID: PMC3379182. 3: Zhang S, Wang Y, Xu H. A new naphthalimide-picolinohydrazide derived fluorescent "turn-on" probe for hypersensitive detection of Al3+ ions and applications of real water analysis and bio-imaging. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Jul 5;275:121193. doi: 10.1016/j.saa.2022.121193. Epub 2022 Mar 24. PMID: 35364410. 4: Yang M, Lee SC, Kim M, Lim MH, Kim C. A multi-functional picolinohydrazide- based chemosensor for colorimetric detection of iron and dual responsive detection of hypochlorite. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Jan 15;245:118899. doi: 10.1016/j.saa.2020.118899. Epub 2020 Sep 2. PMID: 32932033. 5: Khandar AA, Afkhami FA, Krautscheid H, Kristoffersen KA, Atioğlu Z, Akkurt M, Görbitz CH. Crystal structures of di- bromido-{N-[(pyridin-2-yl-κN)methyl- idene]picolinohydrazide-κ2N',O}cadmium methanol monosolvate and di-iodido{N-[(pyridin-2-yl-κN)methyl- idene]picolinohydrazide-κ2N',O}cadmium. Acta Crystallogr E Crystallogr Commun. 2017 Apr 13;73(Pt 5):698-701. doi: 10.1107/S2056989017005308. PMID: 28529779; PMCID: PMC5418787. 6: Zhang Y, Zhou B, Wei P, Liu L, Bai R, Wang Y, Zhou L. Design, bioactivity and mechanism of N'-phenyl pyridylcarbohydrazides with broad-spectrum antifungal activity. Mol Divers. 2025 Apr;29(2):1375-1392. doi: 10.1007/s11030-024-10919-4. Epub 2024 Jun 26. PMID: 38926303. 7: Mondal B. Crystal structure of di-ethyl-ammonium dioxido{Z)-N-[(pyri-din-2-yl)car-bon-yl-azan-idyl]pyri-dine-2-car- box-imid-ato}vana-date(1-) monohydrate. Acta Crystallogr E Crystallogr Commun. 2024 Feb 8;80(Pt 3):277-280. doi: 10.1107/S2056989024001166. PMID: 38456060; PMCID: PMC10915662. 8: Goswami S, Das S, Aich K, Sarkar D, Mondal TK, Quah CK, Fun HK. CHEF induced highly selective and sensitive turn-on fluorogenic and colorimetric sensor for Fe3+. Dalton Trans. 2013 Nov 14;42(42):15113-9. doi: 10.1039/c3dt51974k. Epub 2013 Sep 3. PMID: 24000084. 9: Kumar P, Swain A, Acharya J, Li Y, Kumar V, Rajaraman G, Colacio E, Chandrasekhar V. Synthesis, Structure, and Zero-Field SMM Behavior of Homometallic Dy2, Dy4, and Dy6 Complexes. Inorg Chem. 2022 Aug 1;61(30):11600-11621. doi: 10.1021/acs.inorgchem.2c01041. Epub 2022 Jul 18. PMID: 35849822. 10: Wu SP, Huang ZM, Liu SR, Chung PK. A pyrene-based highly selective turn-on fluorescent sensor for copper(II) ion and its application in live cell imaging. J Fluoresc. 2012 Jan;22(1):253-9. doi: 10.1007/s10895-011-0955-7. Epub 2011 Aug 26. PMID: 21870075. 11: Jiang J, Liang P, Yu H, You Z. Synthesis, Crystal Structures and Urease Inhibition of Mononuclear Copper(II) and Nickel(II) Complexes with Schiff Base Ligands. Acta Chim Slov. 2022 Sep 26;69(3):629-637. doi: 10.17344/acsi.2022.7513. PMID: 36196808. 12: Kitamura F, Sawaguchi K, Mori A, Takagi S, Suzuki T, Kobayashi A, Kato M, Nakajima K. Coordination Structure Conversion of Hydrazone-Palladium(II) Complexes in the Solid State and in Solution. Inorg Chem. 2015 Sep 8;54(17):8436-48. doi: 10.1021/acs.inorgchem.5b01128. Epub 2015 Aug 25. PMID: 26305775. 13: Sarina EA, Olmstead MM, Kanichar D, Groziak MP. A zwitterion produced by a strong intramolecular N→B interaction in 1-hydroxy-2-(pyridin-2-ylcarbonyl)benzo[d][1,2,3]diazaborinine. Acta Crystallogr C Struct Chem. 2015 Dec 1;71(Pt 12):1085-8. doi: 10.1107/S2053229615021841. Epub 2015 Nov 26. PMID: 26632836. 14: Xu L, Zhu J, Shen X, Chai J, Shi L, Wu B, Li W, Ma D. 6-Hydroxy Picolinohydrazides Promoted Cu(I)-Catalyzed Hydroxylation Reaction in Water: Machine-Learning Accelerated Ligands Design and Reaction Optimization. Angew Chem Int Ed Engl. 2024 Dec 20;63(52):e202412552. doi: 10.1002/anie.202412552. Epub 2024 Oct 25. PMID: 39189301. 15: Das S, Das PP, Walton JW, Ghoshal K, Patra L, Bhattacharyya M. An excited state intramolecular proton transfer induced phosphate ion targeted ratiometric fluorescent switch to monitor phosphate ions in human peripheral blood mononuclear cells. Dalton Trans. 2022 Jul 19;51(28):10779-10786. doi: 10.1039/d2dt00581f. PMID: 35611756. 16: Li S, Xu L, An B, Ma D. Assembly of Biaryl Amines via Mild Copper-Catalyzed Coupling of Anilines with (Hetero)aryl Chlorides/Bromides. Org Lett. 2025 Feb 14;27(6):1498-1503. doi: 10.1021/acs.orglett.5c00004. Epub 2025 Jan 31. PMID: 39886867. 17: Gong S, Zhang Y, Qin A, Li M, Gao Y, Zhang C, Song J, Xu X, Wang Z, Wang S. A novel AIE-active camphor-based fluorescent probe for simultaneous detection of Al3+ and Zn2+ at dual channels in living cells and zebrafish. Analyst. 2021 Dec 20;147(1):87-100. doi: 10.1039/d1an01733k. PMID: 34842861. 18: Biswas S, Das S, Gupta T, Singh SK, Pissas M, Rajaraman G, Chandrasekhar V. Observation of Slow Relaxation and Single-Molecule Toroidal Behavior in a Family of Butterfly-Shaped Ln4 Complexes. Chemistry. 2016 Dec 19;22(51):18532-18550. doi: 10.1002/chem.201603640. Epub 2016 Nov 7. PMID: 27943506. 19: Dey S, Sen C, Sinha C. Chromogenic hydrazide Schiff base reagent: Spectrophotometric determination of CN- ion. Spectrochim Acta A Mol Biomol Spectrosc. 2020 Jan 15;225:117471. doi: 10.1016/j.saa.2019.117471. Epub 2019 Aug 15. PMID: 31450225. 20: Li M, Ruan S, Yang H, Zhang Y, Yang Y, Song J, Xu X, Wang Z, Wang S. Nopinone-based AIE-active dual-functional fluorescent chemosensor for Hg2+ and Cu2+ and its environmental and biological applications. Dalton Trans. 2020 Nov 10;49(43):15299-15309. doi: 10.1039/d0dt02888f. PMID: 33112321.