MedKoo Cat#: 414203 | Name: Pidobenzone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pidobenzone is a dermatologic agent that has been used as a treatment for melasma. Pidobenzone has applications as a treatment for solar lentigines.

Chemical Structure

Pidobenzone
Pidobenzone
CAS#138506-45-3

Theoretical Analysis

MedKoo Cat#: 414203

Name: Pidobenzone

CAS#: 138506-45-3

Chemical Formula: C11H11NO4

Exact Mass: 221.0688

Molecular Weight: 221.21

Elemental Analysis: C, 59.73; H, 5.01; N, 6.33; O, 28.93

Price and Availability

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1g USD 4,650.00 4-6 weeks
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Related CAS #
No Data
Synonym
Pidobenzone; K5 lipogel
IUPAC/Chemical Name
5-Oxo-L-proline, p-hydroxyphenyl ester
InChi Key
SDJPNDMWNUPUFI-VIFPVBQESA-N
InChi Code
InChI=1S/C11H11NO4/c13-7-1-3-8(4-2-7)16-11(15)9-5-6-10(14)12-9/h1-4,9,13H,5-6H2,(H,12,14)/t9-/m0/s1
SMILES Code
O=C(OC1=CC=C(O)C=C1)[C@H](CC2)NC2=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Pidobenzone is a dermatologic agent.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 221.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Campanati A, Giannoni M, Scalise A, De Blasio S, Giuliano A, Giuliodori K, Ganzetti G, Bolletta E, Di Benedetto G, Offidani A. Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial. Dermatology. 2016;232(4):478-83. doi: 10.1159/000447356. Epub 2016 Aug 12. PMID: 27513344. 2: Zanieri F, Assad GB, Campolmi P, Lotti T. Melasma: successful treatment with pidobenzone 4% (K5lipogel). Dermatol Ther. 2008 Jul;21 Suppl 1:S18-9. doi: 10.1111/j.1529-8019.2008.00197.x. PMID: 18727811.