MedKoo Cat#: 146070 | Name: Isodienestrol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Isodienestrol is a synthetic compound classified as a nonsteroidal estrogen. It is primarily used in hormone replacement therapy (HRT) and in the treatment of menopausal symptoms, such as hot flashes and vaginal dryness, by mimicking the effects of estrogen in the body. Its mechanism involves binding to estrogen receptors, which activates estrogen-like effects on target tissues, including the reproductive and bone systems.

Chemical Structure

Isodienestrol
Isodienestrol
CAS#35495-11-5

Theoretical Analysis

MedKoo Cat#: 146070

Name: Isodienestrol

CAS#: 35495-11-5

Chemical Formula: C18H18O2

Exact Mass: 266.1300

Molecular Weight: 266.34

Elemental Analysis: C, 81.17; H, 6.81; O, 12.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Isodienestrol;
IUPAC/Chemical Name
4,4'-((2Z,4Z)-hexa-2,4-diene-3,4-diyl)diphenol
InChi Key
NFDFQCUYFHCNBW-XBMAZEBWSA-N
InChi Code
1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3-,18-4-
SMILES Code
C\C=C(C1=CC=C(O)C=C1)/C(=C\C)C2=CC=C(O)C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 266.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sato Y, Murai T, Oda T, Saitô H, Kodama M, Hirata A. Inhibition of microtubule polymerization by synthetic estrogens: formation of a ribbon structure. J Biochem. 1987 May;101(5):1247-52. doi: 10.1093/oxfordjournals.jbchem.a121988. PMID: 3654591. 2: Gruber B, Cohen L, Blix PM. Specific cytosol binding of diethylstilbestrol in rat skeletal muscle. Steroids. 1982 May;39(5):479-95. doi: 10.1016/0039-128x(82)90049-6. PMID: 6755812.