MedKoo Cat#: 128652 | Name: Eleutherin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eleutherin is a type of naphthoquinone derivative with the protective effect against the injury ofhuman umbilical vein endothelial cells (HUVECs), which can be isolated from the edible bulbs of Eleutherine americana (Hong-Cong).

Chemical Structure

Eleutherin
Eleutherin
CAS#478-36-4

Theoretical Analysis

MedKoo Cat#: 128652

Name: Eleutherin

CAS#: 478-36-4

Chemical Formula: C16H16O4

Exact Mass: 272.1049

Molecular Weight: 272.30

Elemental Analysis: C, 70.58; H, 5.92; O, 23.50

Price and Availability

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5mg USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
Eleutherin; (+)-Eleutherin
IUPAC/Chemical Name
(1R,3S)-9-methoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromene-5,10-dione
InChi Key
IAJIIJBMBCZPSW-DTWKUNHWSA-N
InChi Code
InChI=1S/C16H16O4/c1-8-7-11-13(9(2)20-8)16(18)14-10(15(11)17)5-4-6-12(14)19-3/h4-6,8-9H,7H2,1-3H3/t8-,9+/m0/s1
SMILES Code
O=C(C1=C2[C@@H](C)O[C@@H](C)C1)C3=C(C2=O)C(OC)=CC=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 272.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sperry J, Lorenzo-Castrillejo I, Brimble MA, Machín F. Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum. Bioorg Med Chem. 2009 Oct 15;17(20):7131-7. doi: 10.1016/j.bmc.2009.08.064. Epub 2009 Sep 4. PubMed PMID: 19783445. 2: Krishnan P, Bastow KF. Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone. Biochem Pharmacol. 2000 Nov 1;60(9):1367-79. PubMed PMID: 11008131.