MedKoo Cat#: 146050 | Name: Withacoagin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Withacoagin is a bioactive compound derived from the root of Withania somnifera, commonly known as ashwagandha, a plant used in traditional Ayurvedic medicine. It is known for its adaptogenic, anti-inflammatory, and antioxidant properties, helping to manage stress and improve overall health. Withacoagin works by modulating the activity of various enzymes and pathways involved in oxidative stress and inflammation, which contribute to its therapeutic effects. It is commonly used to promote mental well-being, enhance physical endurance, and support immune function, making it a popular ingredient in supplements for stress relief and vitality.

Chemical Structure

Withacoagin
Withacoagin
CAS#119539-81-0

Theoretical Analysis

MedKoo Cat#: 146050

Name: Withacoagin

CAS#: 119539-81-0

Chemical Formula: C28H38O5

Exact Mass: 454.2700

Molecular Weight: 454.61

Elemental Analysis: C, 73.98; H, 8.43; O, 17.60

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Withacoagin;
IUPAC/Chemical Name
(R)-6-((R)-1-hydroxy-1-((5S,8S,9S,10R,13S,14S,17S)-5-hydroxy-10,13-dimethyl-1-oxo-4,5,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl)-3,4-dimethyl-5,6-dihydro-2H-pyran-2-one
InChi Key
UYRXFMXVVKNLDH-VHXUWDKCSA-N
InChi Code
1S/C28H38O5/c1-16-15-23(33-24(30)17(16)2)27(5,31)21-9-8-19-18-10-14-28(32)12-6-7-22(29)26(28,4)20(18)11-13-25(19,21)3/h6-7,10,14,18-21,23,31-32H,8-9,11-13,15H2,1-5H3/t18-,19-,20-,21-,23+,25-,26-,27+,28-/m0/s1
SMILES Code
[H][C@@]12CC[C@]([H])([C@@](C)(O)[C@@]3([H])CC(C)=C(C)C(=O)O3)[C@@]1(C)CC[C@@]4([H])[C@@]2([H])C=C[C@@]5(O)CC=CC(=O)[C@]45C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 454.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jadaun P, Harshithkumar R, Gaikwad SY, Seniya C, Borse S, Gawai AA, Chavan- Gautam P, Tillu G, Mukherjee A. Withania somnifera extracts induced attenuation of HIV-1: a mechanistic approach to restrict viral infection. Virol J. 2023 Aug 3;20(1):173. doi: 10.1186/s12985-023-02130-y. PMID: 37537596; PMCID: PMC10401819.