JSF-4536 is a Mycobacterium tuberculosis inhibitor. JSF-4898 demonstrated significantly improved biological profiles, notably offering submicromolar MIC values versus M. tuberculosis and promising values characterizing the mouse liver microsome stability, aqueous solubility, and mousepharmacokinetic profile.
MedKoo Cat#: 128594
Name: JSF-4536
CAS#: N/A
Chemical Formula: C22H22ClFN2O3
Exact Mass: 416.1303
Molecular Weight: 416.88
Elemental Analysis: C, 63.39; H, 5.32; Cl, 8.50; F, 4.56; N, 6.72; O, 11.51
The following data is based on the product molecular weight 416.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
