MedKoo Cat#: 146040 | Name: Perezone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Perezone is a synthetic compound known for its potential in the treatment of inflammatory and autoimmune diseases. It works by inhibiting the production of pro-inflammatory cytokines and enzymes involved in the inflammatory response, thereby reducing inflammation. Perezone targets specific molecular pathways that regulate immune cell activation and inflammation, making it a valuable therapeutic agent in managing conditions such as rheumatoid arthritis and other chronic inflammatory disorders. Its anti-inflammatory properties help in alleviating symptoms and improving quality of life for patients with these conditions.

Chemical Structure

Perezone
Perezone
CAS#3600-95-1

Theoretical Analysis

MedKoo Cat#: 146040

Name: Perezone

CAS#: 3600-95-1

Chemical Formula: C15H20O3

Exact Mass: 248.1400

Molecular Weight: 248.32

Elemental Analysis: C, 72.55; H, 8.12; O, 19.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Perezone;
IUPAC/Chemical Name
(R)-3-hydroxy-5-methyl-2-(6-methylhept-5-en-2-yl)cyclohexa-2,5-diene-1,4-dione
InChi Key
JZXORCGMYQZBBQ-SNVBAGLBSA-N
InChi Code
1S/C15H20O3/c1-9(2)6-5-7-10(3)13-12(16)8-11(4)14(17)15(13)18/h6,8,10,18H,5,7H2,1-4H3/t10-/m1/s1
SMILES Code
C[C@H](CCC=C(C)C)C1=C(O)C(=O)C(C)=CC1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 248.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: García Méndez MDC, Encarnación-Guevara S, Martínez Batallar ÁG, Gómez- Caudillo L, Bru-Martínez R, Martínez Márquez A, Selles Marchart S, Tovar-Sánchez E, Álvarez-Berber L, Marquina Bahena S, Perea-Arango I, Arellano-García JJ. High variability of perezone content in rhizomes of Acourtia cordata wild plants, environmental factors related, and proteomic analysis. PeerJ. 2023 Nov 15;11:e16136. doi: 10.7717/peerj.16136. PMID: 38025722; PMCID: PMC10656900. 2: Estévez-Carmona MM, Ramírez-Apan MT, Zaragoza-Ojeda M, Vega-Miranda A, Arenas-Huertero F, Reynolds WF, Obregón-Mendoza MA. Perezone and its phenyl glycine derivative induce cytotoxicity via caspases on human glial cancer cells. Nat Prod Res. 2024 Jun;38(11):1823-1833. doi: 10.1080/14786419.2023.2225121. Epub 2023 Jun 21. PMID: 37341748.