CBL-018 is a small molecule compound that has shown promise as a selective inhibitor of the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This enzyme plays a critical role in converting inactive cortisone to active cortisol, influencing metabolic and inflammatory pathways. By inhibiting 11β-HSD1, CBL-018 helps to regulate cortisol levels, potentially improving metabolic functions and reducing inflammation. Its applications are being explored in the treatment of conditions such as obesity, metabolic syndrome, and inflammatory diseases, where cortisol regulation is a key factor in disease progression.
MedKoo Cat#: 145996
Name: CBL-018
CAS#: 2365471-54-9
Chemical Formula: C14H17NO7
Exact Mass: 311.1000
Molecular Weight: 311.29
Elemental Analysis: C, 54.02; H, 5.50; N, 4.50; O, 35.98
The following data is based on the product molecular weight 311.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
