Piperidenafil is a synthetic compound that acts as a selective inhibitor of phosphodiesterase type 5 (PDE5), similar to other drugs in this class, such as sildenafil (Viagra). Its primary application is in the treatment of erectile dysfunction (ED) by enhancing the effects of nitric oxide, which promotes smooth muscle relaxation and improves blood flow to the penis. The mechanism of piperidenafil involves inhibiting PDE5, which normally breaks down cyclic GMP, thus increasing cyclic GMP levels and facilitating vasodilation. This leads to improved erectile function and is beneficial for men with ED, offering a potential therapeutic alternative to other PDE5 inhibitors.
MedKoo Cat#: 145979
Name: Piperidenafil
CAS#: 224788-34-5
Chemical Formula: C22H29N5O4S
Exact Mass: 459.1900
Molecular Weight: 459.57
Elemental Analysis: C, 57.50; H, 6.36; N, 15.24; O, 13.93; S, 6.98
The following data is based on the product molecular weight 459.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
