MedKoo Cat#: 145971 | Name: QUCHIC

Description:

WARNING: This product is for research use only, not for human or veterinary use.

QUCHIC (quinazolinyl-chlorobenzylidene-cyanoimidazole) is a synthetic compound with potential pharmacological applications, particularly in the treatment of cancer and inflammatory diseases. It works by interacting with specific molecular targets to inhibit cancer cell growth, likely through the modulation of cell cycle progression and apoptosis pathways. The compound's mechanism is thought to involve the inhibition of key signaling pathways, such as those involved in cell proliferation and survival, making it a candidate for targeted cancer therapy. Additionally, QUCHIC’s anti-inflammatory properties may be beneficial in managing chronic inflammatory conditions.

Chemical Structure

QUCHIC
QUCHIC
CAS#1400742-42-8

Theoretical Analysis

MedKoo Cat#: 145971

Name: QUCHIC

CAS#: 1400742-42-8

Chemical Formula: C25H24N2O2

Exact Mass: 384.1800

Molecular Weight: 384.48

Elemental Analysis: C, 78.10; H, 6.29; N, 7.29; O, 8.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
QUCHIC;
IUPAC/Chemical Name
quinolin-8-yl 1-(cyclohexylmethyl)-1H-indole-3-carboxylate
InChi Key
RHYGTJXOHOGQGI-UHFFFAOYSA-N
InChi Code
1S/C25H24N2O2/c28-25(29-23-14-6-10-19-11-7-15-26-24(19)23)21-17-27(16-18-8-2-1-3-9-18)22-13-5-4-12-20(21)22/h4-7,10-15,17-18H,1-3,8-9,16H2
SMILES Code
O=C(OC1=C2N=CC=CC2=CC=C1)C3=CN(CC4CCCCC4)C5=CC=CC=C35
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 384.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Carlier J, Diao X, Huestis MA. Synthetic cannabinoid BB-22 (QUCHIC): Human hepatocytes metabolism with liquid chromatography-high resolution mass spectrometry detection. J Pharm Biomed Anal. 2018 Aug 5;157:27-35. doi: 10.1016/j.jpba.2018.05.007. Epub 2018 May 7. PMID: 29754040. 2: De Luca MA, Castelli MP, Loi B, Porcu A, Martorelli M, Miliano C, Kellett K, Davidson C, Stair JL, Schifano F, Di Chiara G. Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135. Neuropharmacology. 2016 Jun;105:630-638. doi: 10.1016/j.neuropharm.2015.11.017. Epub 2015 Dec 11. PMID: 26686391.