Quazolast | CAS#86048-40-0 | mast cell stabilizer

MedKoo Cat#: 461299 | Name: Quazolast

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quazolast is a mast cell stabilizer and a potent mediator release inhibitor.

Chemical Structure

Quazolast

CAS#86048-40-0

Theoretical Analysis

MedKoo Cat#: 461299

Name: Quazolast

CAS#: 86048-40-0

Chemical Formula: C12H7ClN2O3

Exact Mass: 262.0145

Molecular Weight: 262.64

Elemental Analysis: C, 54.88; H, 2.69; Cl, 13.50; N, 10.67; O, 18.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Quazolast; RHC 3988; RHC-3988; RHC3988;

IUPAC/Chemical Name

methyl 5-chlorooxazolo[4,5-h]quinoline-2-carboxylate

InChi Key

ZCRBUWNCWCWRGL-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H7ClN2O3/c1-17-12(16)11-15-8-5-7(13)6-3-2-4-14-9(6)10(8)18-11/h2-5H,1H3

SMILES Code

O=C(C1=NC2=CC(Cl)=C3C=CC=NC3=C2O1)OC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 262.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fitzpatrick LR, Decktor DL. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. PubMed PMID: 1683105. 2: Dave NK, McMahon SC, Grubbe RE, Bewtra AK, Hopp RJ, Nair NM, Smith J, Townley RG. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302. PubMed PMID: 2221488.