MedKoo Cat#: 145955 | Name: AZD-1134

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZD-1134 is a selective herbicide used in agriculture for controlling a variety of broadleaf and grassy weeds in crops like cereals and soybeans. It works by inhibiting the enzyme acetolactate synthase (ALS), which is involved in the biosynthesis of essential amino acids, disrupting protein synthesis and leading to weed death. This targeted action makes AZD-1134 effective against resistant weeds while minimizing impact on the crops. It is applied to control weed growth, ensuring better crop yield by reducing competition for nutrients, light, and water.

Chemical Structure

AZD-1134
AZD-1134
CAS#442548-99-4

Theoretical Analysis

MedKoo Cat#: 145955

Name: AZD-1134

CAS#: 442548-99-4

Chemical Formula: C28H32FN5O4

Exact Mass: 521.2400

Molecular Weight: 521.59

Elemental Analysis: C, 64.48; H, 6.18; F, 3.64; N, 13.43; O, 12.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
AZD1134; AZD 1134; AZD-1134;
IUPAC/Chemical Name
6-fluoro-8-(4-methylpiperazin-1-yl)-4-oxo-N-(4-(4-propionylpiperazin-1-yl)phenyl)-4H-chromene-2-carboxamide
InChi Key
CKBARMWSFIJZTL-UHFFFAOYSA-N
InChi Code
1S/C28H32FN5O4/c1-3-26(36)34-14-12-32(13-15-34)21-6-4-20(5-7-21)30-28(37)25-18-24(35)22-16-19(29)17-23(27(22)38-25)33-10-8-31(2)9-11-33/h4-7,16-18H,3,8-15H2,1-2H3,(H,30,37)
SMILES Code
CCC(=O)N1CCN(CC1)C2=CC=C(NC(=O)C3=CC(=O)C4=CC(F)=CC(N5CCN(C)CC5)=C4O3)C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 521.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Maier DL, Sobotka-Briner C, Ding M, Powell ME, Jiang Q, Hill G, Heys JR, Elmore CS, Pierson ME, Mrzljak L. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy. J Pharmacol Exp Ther. 2009 Jul;330(1):342-51. doi: 10.1124/jpet.109.150722. Epub 2009 Apr 28. PMID: 19401496.