Nornalmefene is a metabolite of nalmefene, a drug used in the treatment of alcohol dependence. Nornalmefene acts as a selective opioid receptor antagonist, particularly at the μ-opioid receptor, which plays a significant role in reducing the reinforcing effects of alcohol consumption. Its mechanism involves modulating the brain's reward system, thereby decreasing cravings and promoting abstinence in individuals with alcohol use disorder. Nornalmefene is mainly studied for its potential to help manage alcohol dependence, as well as for its effects on other addictive behaviors.
MedKoo Cat#: 145899
Name: Nornalmefene
CAS#: 42971-33-5
Chemical Formula: C17H19NO3
Exact Mass: 285.1400
Molecular Weight: 285.34
Elemental Analysis: C, 71.56; H, 6.71; N, 4.91; O, 16.82
The following data is based on the product molecular weight 285.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
