Kurchinin is a non-alkaloidal compound found in the bark of Holarrhena pubescens, a plant traditionally used in various medicinal applications. Studies have demonstrated that kurchinin exhibits antioxidant and antidiabetic activities, suggesting its potential as a therapeutic agent for managing oxidative stress and diabetes. The compound's mechanism of action is believed to involve the inhibition of α-glucosidase, an enzyme responsible for carbohydrate digestion, thereby delaying glucose absorption and preventing postprandial hyperglycemia. Additionally, kurchinin's antioxidant properties may help mitigate oxidative damage associated with diabetes.
MedKoo Cat#: 145833
Name: Kurchinin
CAS#: 7801-18-5
Chemical Formula: C19H24O3
Exact Mass: 300.1700
Molecular Weight: 300.40
Elemental Analysis: C, 75.97; H, 8.05; O, 15.98
The following data is based on the product molecular weight 300.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
