MedKoo Cat#: 145741 | Name: Garbanzol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Garbanzol is a flavanonol, a type of flavonoid. This compound has been studied for its potential in enhancing the production of fisetin, a flavonoid known for its antioxidant properties. Research indicates that adding garbanzol to cultures can increase fisetin yields, suggesting a role in metabolic engineering for flavonoid biosynthesis.

Chemical Structure

Garbanzol
Garbanzol
CAS#1226-22-8

Theoretical Analysis

MedKoo Cat#: 145741

Name: Garbanzol

CAS#: 1226-22-8

Chemical Formula: C15H12O5

Exact Mass: 272.0700

Molecular Weight: 272.26

Elemental Analysis: C, 66.17; H, 4.44; O, 29.38

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Garbanzol;
IUPAC/Chemical Name
(2R,3R)-3,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
InChi Key
VRTGGIJPIYOHGT-LSDHHAIUSA-N
InChi Code
1S/C15H12O5/c16-9-3-1-8(2-4-9)15-14(19)13(18)11-6-5-10(17)7-12(11)20-15/h1-7,14-17,19H/t14-,15+/m0/s1
SMILES Code
O[C@@H]1[C@H](OC2=CC(O)=CC=C2C1=O)C3=CC=C(O)C=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 272.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Marín L, Gutiérrez-Del-Río I, Villar CJ, Lombó F. De novo biosynthesis of garbanzol and fustin in Streptomyces albus based on a potential flavanone 3-hydroxylase with 2-hydroxylase side activity. Microb Biotechnol. 2021 Sep;14(5):2009-2024. doi: 10.1111/1751-7915.13874. Epub 2021 Jul 3. PMID: 34216097; PMCID: PMC8449655. 2: Saejueng K, Panthama N. Radical scavenging activities of flavonoids from roots of Akschindlium godefroyanum. Nat Prod Res. 2015;29(12):1177-9. doi: 10.1080/14786419.2014.983103. Epub 2014 Nov 26. PMID: 25426867. 3: Stahlhut SG, Siedler S, Malla S, Harrison SJ, Maury J, Neves AR, Forster J. Assembly of a novel biosynthetic pathway for production of the plant flavonoid fisetin in Escherichia coli. Metab Eng. 2015 Sep;31:84-93. doi: 10.1016/j.ymben.2015.07.002. Epub 2015 Jul 17. PMID: 26192693. 4: Chen H, Wang C, Zhou H, Tao R, Ye J, Li W. Antioxidant capacity and identification of the constituents of ethyl acetate fraction from Rhus verniciflua Stokes by HPLC-MS. Nat Prod Res. 2017 Jul;31(13):1573-1577. doi: 10.1080/14786419.2016.1277353. Epub 2017 Jan 18. PMID: 28100074. 5: Chen Q, Wang X, Yuan X, Shi J, Zhang C, Yan N, Jing C. Comparison of Phenolic and Flavonoid Compound Profiles and Antioxidant and α-Glucosidase Inhibition Properties of Cultivated Soybean (Glycine max) and Wild Soybean (Glycine soja). Plants (Basel). 2021 Apr 20;10(4):813. doi: 10.3390/plants10040813. PMID: 33924154; PMCID: PMC8074397. 6: Jin MJ, Kim IS, Park JS, Dong MS, Na CS, Yoo HH. Pharmacokinetic Profile of Eight Phenolic Compounds and Their Conjugated Metabolites after Oral Administration of Rhus verniciflua Extracts in Rats. J Agric Food Chem. 2015 Jun 10;63(22):5410-6. doi: 10.1021/acs.jafc.5b01724. Epub 2015 May 29. PMID: 25998231. 7: Ango PY, Kapche DW, Fotso GW, Fozing CD, Yeboah EM, Mapitse R, Demirtas I, Ngadjui BT, Yeboah SO. Thonningiiflavanonol A and thonningiiflavanonol B, two novel flavonoids, and other constituents of Ficus thonningii Blume (Moraceae). Z Naturforsch C J Biosci. 2016 Mar;71(3-4):65-71. doi: 10.1515/znc-2015-0147. PMID: 26959540. 8: Chen H, Zhou H, Tao R, Li W, Wang CZ. Simultaneous quantification of six flavonoids of Rhus verniciflua Stokes using matrix solid-phase dispersion via high-performance liquid chromatography coupled with photodiode array detector. J Sep Sci. 2020 Dec;43(23):4281-4288. doi: 10.1002/jssc.202000749. Epub 2020 Oct 15. PMID: 32991034. 9: Xie Y, Zhang W, Duan X, Dai C, Zhang Y, Cui W, Wang R, Shen W. Hydrogen-rich water-alleviated ultraviolet-B-triggered oxidative damage is partially associated with the manipulation of the metabolism of (iso)flavonoids and antioxidant defence in Medicago sativa. Funct Plant Biol. 2015 Dec;42(12):1141-1157. doi: 10.1071/FP15204. PMID: 32480752. 10: Park KY, Jung GO, Lee KT, Choi J, Choi MY, Kim GT, Jung HJ, Park HJ. Antimutagenic activity of flavonoids from the heartwood of Rhus verniciflua. J Ethnopharmacol. 2004 Jan;90(1):73-9. doi: 10.1016/j.jep.2003.09.043. PMID: 14698512.