BMS-986318 is primarily known as a selective inhibitor of Bruton's tyrosine kinase (BTK). BTK plays a critical role in the development and function of B cells, which are part of the immune system. By inhibiting BTK, BMS-986318 aims to treat various autoimmune diseases and B-cell malignancies such as rheumatoid arthritis and certain types of lymphoma.
MedKoo Cat#: 145728
Name: BMS-986318
CAS#: 2314378-09-9
Chemical Formula: C30H23Cl2F3N4O3
Exact Mass: 614.1100
Molecular Weight: 615.43
Elemental Analysis: C, 58.55; H, 3.77; Cl, 11.52; F, 9.26; N, 9.10; O, 7.80
The following data is based on the product molecular weight 615.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
