MedKoo Cat#: 128533 | Name: Seldegamadlin
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Seldegamadlin is an E3 ubiquitin-protein ligase Mdm2 (Hdm2) degrader.

Chemical Structure

Seldegamadlin
Seldegamadlin
CAS# 2713618-08-5

Theoretical Analysis

MedKoo Cat#: 128533

Name: Seldegamadlin

CAS#: 2713618-08-5

Chemical Formula: C48H52Cl2FN7O6

Exact Mass: 911.3340

Molecular Weight: 912.89

Elemental Analysis: C, 63.15; H, 5.74; Cl, 7.77; F, 2.08; N, 10.74; O, 10.52

Price and Availability

Size Price Availability Quantity
1mg USD 950.00 2 Weeks
5mg USD 1,650.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Seldegamadlin; Seldegamadlinum; KT-253; KT 253; KT253;
IUPAC/Chemical Name
(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-((1R,4R)-4-(4-(1-((R)-2,6-dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)piperidine-1-carbonyl)cyclohexyl)-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide
InChi Key
CQFHGOWYJXQICA-QUILVXKMSA-N
InChi Code
InChI=1S/C48H52Cl2FN7O6/c1-56-37-24-28(10-15-35(37)58(46(56)64)36-16-17-38(59)54-42(36)60)26-18-22-57(23-19-26)44(62)27-8-12-30(13-9-27)52-43(61)41-39(31-6-5-7-33(50)40(31)51)48(47(55-41)20-3-2-4-21-47)32-14-11-29(49)25-34(32)53-45(48)63/h5-7,10-11,14-15,24-27,30,36,39,41,55H,2-4,8-9,12-13,16-23H2,1H3,(H,52,61)(H,53,63)(H,54,59,60)/t27-,30-,36-,39+,41-,48-/m1/s1
SMILES Code
ClC1=CC=CC([C@]2([H])[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C5(CCCCC5)N[C@@]2([H])C(N[C@]6(CC[C@@](C(N7CCC(C8=CC(N(C)C(N9[C@@]%10([H])C(NC(CC%10)=O)=O)=O)=C9C=C8)CC7)=O)([H])CC6)[H])=O)=C1F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 912.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL