MedKoo Cat#: 128409 | Name: Octyl Gallate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Octyl gallate is an antioxidant, antibacterial, and antifungal agent.

Chemical Structure

Octyl Gallate
Octyl Gallate
CAS#1034-01-1

Theoretical Analysis

MedKoo Cat#: 128409

Name: Octyl Gallate

CAS#: 1034-01-1

Chemical Formula: C15H22O5

Exact Mass: 282.1467

Molecular Weight: 282.34

Elemental Analysis: C, 63.81; H, 7.85; O, 28.33

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
25g USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
Octyl Gallate; Gallic Acid octyl ester; n-Octyl Gallate; Progallin O; n-Octylgallate; NSC 97419; NSC97419; NSC-97419;
IUPAC/Chemical Name
octyl 3,4,5-trihydroxybenzoate
InChi Key
NRPKURNSADTHLJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H22O5/c1-2-3-4-5-6-7-8-20-15(19)11-9-12(16)14(18)13(17)10-11/h9-10,16-18H,2-8H2,1H3
SMILES Code
O=C(C1=CC(O)=C(C(O)=C1)O)OCCCCCCCC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 282.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Haute GV, Luft C, Pedrazza L, Donadio MVF, de Oliveira JR. Octyl gallate decrease lymphocyte activation and regulates neutrophil extracellular traps release. Mol Biol Rep. 2022 Feb;49(2):1593-1599. doi: 10.1007/s11033-021-06937-2. Epub 2021 Nov 16. PMID: 34783987. 2: Su M, Yin B, Xing X, Li Z, Zhang J, Feng S, Li L, Zhao F, Yang X, Yu S, Wang J, Zhang Y, Shi D, Chen J, Feng L, Guo D, Sun D. Octyl gallate targeting the 3C-like protease exhibits highly efficient antiviral activity against swine enteric coronavirus PEDV. Vet Microbiol. 2023 Jun;281:109743. doi: 10.1016/j.vetmic.2023.109743. Epub 2023 Apr 11. PMID: 37062110. 3: Park H, Ko R, Seo J, Ahn GY, Choi SW, Kwon M, Lee SY. Octyl gallate has potent anti-inflammasome activity by directly binding to NLRP3 LRR domain. J Cell Physiol. 2024 Apr;239(4):e31196. doi: 10.1002/jcp.31196. Epub 2024 Jan 19. PMID: 38240115. 4: Qiu C, Lu Y, Gu H, Jia M, Wang J, Zhang Q, Lv L. Food additive octyl gallate eliminates acrolein and inhibits bacterial growth in oil-rich food. Food Chem. 2022 Nov 30;395:133546. doi: 10.1016/j.foodchem.2022.133546. Epub 2022 Jun 20. PMID: 35802979. 5: Vijayalakshmi P, Indu S, Ireen C, Manjunathan R, Rajalakshmi M. Octyl Gallate and Gallic Acid Isolated from Terminalia bellirica Circumvent Breast Cancer Progression by Enhancing the Intrinsic Apoptotic Signaling Pathway and Elevating the Levels of Anti-oxidant Enzymes. Appl Biochem Biotechnol. 2023 Dec;195(12):7214-7235. doi: 10.1007/s12010-023-04450-9. Epub 2023 Mar 29. PMID: 36988844. 6: Wang Q, Zhang Y, Li H. Octyl gallate: An antioxidant demonstrating selective and sensitive fluorescent property. Food Chem. 2017 Mar 15;219:268-273. doi: 10.1016/j.foodchem.2016.09.157. Epub 2016 Sep 28. PMID: 27765226. 7: Avuloglu Yilmaz E, Yuzbasioglu D, Unal F. Investigation of genotoxic effect of octyl gallate used as an antioxidant food additive in in vitro test systems. Mutagenesis. 2023 Jun 20;38(3):151-159. doi: 10.1093/mutage/gead005. PMID: 36882025; PMCID: PMC10281373. 8: Eler GJ, Santos IS, de Moraes AG, Comar JF, Peralta RM, Bracht A. n-Octyl gallate as inhibitor of pyruvate carboxylation and lactate gluconeogenesis. J Biochem Mol Toxicol. 2015 Apr;29(4):157-64. doi: 10.1002/jbt.21680. Epub 2014 Dec 8. PMID: 25487712. 9: Lima KG, Schneider Levorse VG, Rosa Garcia MC, de Souza Basso B, Pasqualotto Costa B, Antunes GL, Luft C, Haute GV, Leal Xavier L, Donadio MVF, Rodrigues de Oliveira J. Octyl gallate induces hepatic steatosis in HepG2 cells through the regulation of SREBP-1c and PPAR-gamma gene expression. EXCLI J. 2020 Jul 6;19:962-971. doi: 10.17179/excli2020-2214. PMID: 32788910; PMCID: PMC7415935. 10: Chua KV, Fan CS, Chen CC, Chen LL, Hsieh SC, Huang TS. Octyl Gallate Induces Pancreatic Ductal Adenocarcinoma Cell Apoptosis and Suppresses Endothelial- Mesenchymal Transition-Promoted M2-Macrophages, HSP90α Secretion, and Tumor Growth. Cells. 2019 Dec 30;9(1):91. doi: 10.3390/cells9010091. PMID: 31905895; PMCID: PMC7016987.